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1、山東輕工業(yè)學(xué)院2012屆本科畢業(yè)設(shè)計(jì)(論文)摘要本設(shè)計(jì)采用濕法制粒壓片,主要生產(chǎn)工序?yàn)榉鬯?、篩分、混合、制粒、干燥、壓片、包衣、包裝。然后根據(jù)生產(chǎn)工序進(jìn)行物料衡算與能量衡算。物料衡算應(yīng)考慮到每一步生產(chǎn)工序產(chǎn)生的損失,從最后一步開始,往前面的工序推進(jìn)來進(jìn)行計(jì)算。物料衡算確定了原材料消耗定額,從而確定了設(shè)備工藝設(shè)計(jì)與選型,進(jìn)而決定管路設(shè)計(jì)等各種設(shè)計(jì)項(xiàng)目。再者就是能量衡算,涉及到生產(chǎn)工序中的干燥及冷卻需要消耗循環(huán)水的熱量。能量衡算還包括每臺(tái)設(shè)備在生產(chǎn)中消耗的電能。選擇廠址時(shí),周圍應(yīng)有良好的衛(wèi)生環(huán)境,空氣污染少,無水土污染的地區(qū),也
2、要盡量避免人流,物流比較密集的工業(yè)區(qū)域。廠址的交通運(yùn)輸應(yīng)方便、快捷,水,電汽,原材料和燃料的供應(yīng)要方便。車間應(yīng)按工藝流程合理布局,有利于生產(chǎn)操作,并能保證對(duì)生產(chǎn)過程進(jìn)行有效的管理。正確劃分生產(chǎn)工藝流程中生產(chǎn)區(qū)域的潔凈級(jí)別,避免生產(chǎn)流程的迂回和人、物流交叉等。制藥用水的制備以飲用為原料,經(jīng)逐級(jí)提純水質(zhì)。最后應(yīng)做好廠區(qū)及車間的安全衛(wèi)生工作,并處理好生產(chǎn)過程中產(chǎn)生的“三廢”。關(guān)鍵詞:拉莫三嗪工藝設(shè)計(jì)工藝流程片劑生產(chǎn)AbstractThedesignusesthewetgranulationtotablet,themainprodu
3、ctionprocessescontaincrushing,sieving,mixing,granulating,drying,pressing,coatingandpackaging.Theconsiderationofthematerialbalanceandtheenergybalanceisdependontheproductionprocess.Materialbalanceconsiderationshouldbecalculatedfromthelaststeptotheformer,takingintoacc
4、ountofeachstepoflossineveryproductionprocesses.Materialbalancecalculationdeterminestherawmaterialconsumptionquota,theprocessdesignandselectionofequipment,soasthepipelinedesignandotherdesignprojects.Furthermore,relatedtothedryingandcoolingoftheproductionprocess,thee
5、nergybalanceshouldconsumeheatconsumptionofthecirculatingwater.Energybalancealsoincludestheelectricenergyconsumptionofeachequipmentintheproduction.Thesurroundingenvironmentshouldbefavorable,havinglessairpollutionandnosoilpollution,avoidingindustrialareathatpeopleand
6、materialsintensivewhenchoosingthelocationofafactory.Thesiteshouldbeconvenient,applyingadequatewater,electricity,steamandrawmaterials.Thearrangementofworkplaceshouldbesuitableonthebasisoftheprocess,facilitatethe32山東輕工業(yè)學(xué)院2012屆本科畢業(yè)設(shè)計(jì)(論文)productionoperation,andcanguara
7、nteetheeffectivemanagementtotheproductionprocess,correctlydividingproductionprocessproductionareacleanlevel,avoidingtheproductionprogressroundabout,peopleandlogisticscrossover.Thedrinkingwaterisusedastherawmaterialforthehepreparationofpharmaceuticalwater,throughste
8、pwiseprocesstopurifythewaterquality.Finally,itshouldhandlethesafetyandhealthoffactoryandworkplace,anddealwiththe"threewastes"intheproductionproce