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1、中國組織工程研究笫，8謄第73期2014—03—26出版ChineseJournalofTissueEngmeefingResearchMarch26,2014Vo1．18,No．13www．CRTER．orgAdministrationofaspirinandrivaroxabanpreventsdeepveinthrombosisaertotalkneearthroplastyzouYue，TianShao·qi，WangYuan-he，LiuJiang-jun，SunKangDepartmentofJointSurgery,theAfiliatedHospitalofQmgdaoU
2、niversity,Qingdao266003，ShandongProvince，ChinaAbstractBACKGROUND：Todate，rivaroxabanhasbeenaclinicallycommonanticoagulantinChina；however，efectiveZouYue．Studyingforprophylaxisforvenousthrombosisisassociatedwithamarkedlyhigherincidenceofperioperativehemorrhagicmaster’sdegree，DepartmentofJointSurgery
3、,theAffiliatedcomplications．Althoughithasbeenreportedthataspirinefectivelypreventsdeepveinthrombosisandpulmona~embolism，theuseofaspirinasaroutinedrugforvenousthrombosisaftertotalkneearthroplastyisHospitalofQingdaoUniversity,Qingdao266003．stillcontroversia1．ShandongProvince，ChinaOBJECTIVE：Tocompar
4、etheeficacyandsafetvofaspirinandrivaroxabanforpreventionofdeepveinthrombosisaftertotaIkneearthroplasty．Correspondingauthor：SunMETHODS：Totally324patientswithosteoarthritiswhounderwentprimaryunilateraItotalkneearthroplastyKang，MD．。Chiefphysician，wererandomlydividedintothreegroups．Twelvehoursafterth
5、esurgery，threegroupsweregivenaspirin，Doctoralsupervisor,rivaroxabanandlow-molecular-weightheparinrespectively．Allthreegroupsweretreatedfor14days．andallofDepartmentofJointSurgery,thepatientswerefoIlowedfor4weeks．theAft]liatedHospitalofRESULTSANDCONCLUS10N：ComparedwiththeIow-mOlecuIar-weIghtheparin
6、group，theIncidenceofdeepQingdaoUniversity,Qingdaoveinthrombosiswaslower(P<0．05)，buthiddenbloodlOSSandwoundcomplicationsweremorecommon(P<266003，ShandongProvinceChina0．051intherivaroxabangroup．TherewerenosignificantdifferencesbetweentheIow-molecular—weighIheparingroupandaspiringroupintheincidenceof
7、deepveinthrombosis，hiddenbloodlOSS，woundcomplicationsordoi：103969／]．issn．2095-4344incidencasoflowerIimbswellingandsubcutaneousecchymosis(P>0．O5)．Theresultsconfirmedthat201413008rivaroxabanhasapositiveantic0aauIati0nefe
