芍甘顆粒提取、精制工藝線路設(shè)計

芍甘顆粒提取、精制工藝線路設(shè)計

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時間:2018-07-28

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1、中藥制藥分離工程課程設(shè)計目錄1.設(shè)計任書···················································032.設(shè)計概述···················································042.1處方··················································042.2用法··················································042.3功能主治·····························

2、··················042.4藥理作用···············································042.5顆粒劑介紹·············································053.常用精制技術(shù)簡介············································063.1常用精制分離方法······································0621中藥制藥分離工程課程設(shè)計3.2簡析·························

3、··························064.課程實驗····················································085.工藝路線設(shè)計················································155.1處方···················································155.2制備工藝···············································155.3工藝流程及工藝說明··········

4、···························165.3.1工藝流程···········································165.3.2工藝說明···········································175.4提取物生產(chǎn)過程數(shù)據(jù)表····································186.結(jié)束語21中藥制藥分離工程課程設(shè)計·····················································197.參考文獻··············

5、·····································19設(shè)計任務(wù)書一、設(shè)計題目芍甘湯提取、精制工藝設(shè)計水提醇沉二、設(shè)計條件(1)芍甘復(fù)方顆粒劑提取物二、設(shè)計內(nèi)容與要求(1)確定提取工藝及參數(shù);(2)確定精制分離工藝及參數(shù);(3)提取物得率、成分含量以及相對密度;(5)編寫設(shè)計說明書;三、設(shè)計成果(1)設(shè)計說明書一份包括概述(簡要說明所設(shè)計的復(fù)方中藥效物質(zhì)成分類型、性質(zhì)及藥理作用等);常用精制分離技術(shù)簡述(主要為高速離心、醇沉、大孔樹脂吸附以及超濾)課程實驗(不同精制方法的效果及比較);工藝線路的設(shè)計(從最終制劑的劑型、工藝合理性以及生產(chǎn)

6、成本等方面考慮)。(2)芍甘湯提取精制工藝流程圖;21中藥制藥分離工程課程設(shè)計四、設(shè)計時間設(shè)計時間為2周,從2013年5月12日至2013年5月26日。一、概述1、處方組成甘草12g芍藥12g芍藥【來源】本品為毛茛科植物芍藥PaeonialactifloraPall.的干燥根。夏、秋二季采挖,洗凈,除去頭尾和細根,置沸水中煮后除去外皮或去皮后再煮,曬干?!舅幮浴靠?、酸,微寒。歸肝、脾經(jīng)?!竟πА筐B(yǎng)血調(diào)經(jīng),斂陰止汗,柔肝止痛,平抑肝陽?!局髦巍坑糜谘撐S,月經(jīng)不調(diào),自汗,盜汗,脅痛,腹痛,四肢攣痛,頭痛眩暈。甘草【來源】本品為豆科植物甘草Glycyrrhiz

7、auralensisFisch.、脹果甘草GlycyrrhizainflataBat.或光果甘草GlycyrrhizaglabraL.的干燥根和根莖。春、秋二季采挖,除去須根,曬干?!舅幮浴扛?,平。歸心、肺、脾、胃經(jīng)?!竟πА垦a脾益氣,清熱解毒,祛痰止咳,緩急止痛,調(diào)和諸藥?!局髦巍坑糜谄⑽柑撊酰氲》α?,心悸氣短,咳嗽痰多,脘腹、四肢攣急疼痛,癰腫瘡毒,緩解藥物毒性、烈性。2、用法21中藥制藥分離工程課程設(shè)計取上述2味,加600mL水煎煮至300mL,取液去渣,溫服。3、功能主治本方主治津液受損,陰血不足,筋脈失濡所致諸證。由芍藥和甘草組成;方中芍藥酸寒,

8、養(yǎng)血斂陰,柔肝止痛;甘草甘溫,健脾益氣,緩急止痛。二

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