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1、健肺膠囊治療慢性阻塞性肺疾病穩(wěn)定期療效觀(guān)察作者:郭文新張鳳宇閻國(guó)良【摘要】 目的觀(guān)察健肺膠囊對(duì)慢性阻塞性肺疾病(COPD)穩(wěn)定期的臨床療效、中醫(yī)證候積分及6min步行距離的影響。方法將100例COPD穩(wěn)定期患者隨機(jī)分為2組,對(duì)照組50例予氧療、身體鍛煉、口服茶堿制劑及沐舒坦、吸入長(zhǎng)效β2受體激動(dòng)劑等西醫(yī)常規(guī)基礎(chǔ)治療,治療組50例在對(duì)照組治療基礎(chǔ)上加用自擬健肺膠囊,每次2~3粒,每日3次口服。2組均14日為1個(gè)療程,治療2個(gè)療程。觀(guān)察2組治療前后中醫(yī)證候積分及6min步行距離,并判定臨床療效。結(jié)果①臨床療效:治療組總有效率96%,對(duì)照組總有效率84%,治療組
2、療效明顯優(yōu)于對(duì)照組(P<0.05);②中醫(yī)證候積分:2組治療后與治療前比較差異均有統(tǒng)計(jì)學(xué)意義(P<0.01),且2組治療后比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05);③6min步行距離:2組治療后均較治療前改善(P<0.05),2組治療后比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論健肺膠囊對(duì)COPD穩(wěn)定期患者的臨床療效、癥狀、體征及勞動(dòng)耐力均有明顯改善?!娟P(guān)鍵詞】肺疾病阻塞性膠囊劑慢性病補(bǔ)肺隨機(jī)對(duì)照試驗(yàn)中西醫(yī)結(jié)合療法10 ClinicalobservationofthetherapeuticeffectofJianfeicapsuleonchro
3、nicobstructivepulmonarydiseaseatstationaryphase 【Abstract】ObjectiveToobservethetherapeuticeffectofJianfeicapsuleonchronicobstructivepulmonarydiseaseatstationaryphaseaswellastheTCMscoringofsymptomsandtheeffectofindexof6-mindistancewalk.Methods100casedwithchronicobstructivepulmonary
4、diseasewererandomlydividedinto2groupswith50ineach.ThecontrolgroupwastreatedbyroutinemedicaltreatmentlikeoxygentherapyandphysicalexercisewiththeophyllineandMucosolvan,inhalinglong-termβ2receptorstimulatingagent.Thetreatmentgroupwas,onthebasisofcontrolgroup,treatedbyJianfeicapsule,2~
5、3pillseachtime,3timesadayperos.Bothgroupshavethetreatmentcourseof28days(14daysforeverycourse).TheTCMscoringandtheindexof6-minwalkinginbothgroupswereevaluated.Results①TherapeuticEffect:thetotaleffectiverateintreatmentgroupwas96%,whichwas84%incontrolgroup.Theformergroupwasobviouslysu
6、periortothelatterone(P<0.05)②TCMScoring:therewasasignificantdifferencebetweentwogroupsbeforeandafterthetreatment(P<0.01).Therewasa10significantdifferencebetweentwogroupsafterthetreatment(P<0.05)③6-minDistanceWalking:bothgroupswereimprovedcomparedwiththeformerstate(P<0.0
7、5),therewasasignificantdifferencebetweencontrolgroupandtreatmentgroupafterthetreatment(P<0.05).ConclusionJianfeicapsuleiseffectiveintreatingchronicobstructivepulmonarydiseaseatstationaryphase. 【KeyWords】Pulmonarydisease;Obstructive;Capsule;Chronicdisease;Tonifyingthelung;Random
8、controltest;Integratedther