膠原基納米骨復(fù)合重組人骨形成蛋白2及鈦膜修復(fù)即刻鈦種植體周圍骨缺損

膠原基納米骨復(fù)合重組人骨形成蛋白2及鈦膜修復(fù)即刻鈦種植體周圍骨缺損

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膠原基納米骨復(fù)合重組人骨形成蛋白2及鈦膜修復(fù)即刻鈦種植體周圍骨缺損_第1頁(yè)
膠原基納米骨復(fù)合重組人骨形成蛋白2及鈦膜修復(fù)即刻鈦種植體周圍骨缺損_第2頁(yè)
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1、中國(guó)組織工程研究與臨床康復(fù)第73謄勞29200907—16出版JournalofClinicalRehabilitative~ssueEngineeringResearchJuly16,2009Vo1.73,No.29翟震8asicEx。er_memNano-hydroxyapatite,COIIagencompositedwithrecombinanthumanbonemorphogenetiCprotein·2andtitaniummembraneinrepairingperipheralbonedef

2、ectsofinstantdentalimplants☆LiuBing’ChenPeng,WangZhong.yi。KeJie’LiXiao—hua’WangZheng—wen’,,,,AbstractBACKGROUND:Recently.withtherapiddevelopmentofmateriaIscienceandbioscience.thetechnologyofdentalimplanthasDepartmentofStomatology,madegreatprogress,especial

3、lytheimmediateimplanttechnologyButthesizeandshapeofimplantareusualynotfitfortoothChinesePLAextractionwound.soitisanimportantfactorthatleadstofailurewhenimplantandtoothextractionwoundcannotformcloseGenera1HospitaloftangencyGuidedboneregenerationorbonegrafti

4、ngmaterialsareusuallyusedtosolvethisproblemAirForceBeijing100036,China:0BJECTlVE:Tostudytheeffectsofnano—hydroxyapatite/collogen(nHAC)withrecombinanthumanbonemorphogeneticDepartmentofOraIandMaxilofaciaJprotein一2(rhBMP一2)andtitanium(Ti)membraneonrepairingpe

5、ripheralbonedefectsofinstantimplantSurgery,ChineseDESIGN.TIMEANDSETTING:Arandomized.controledanimaIstudywasperformedattheCentralLaboratory.theFourthPLAGeneraIMilitaryMedicaIUniversityofChinesePLAbetweenJanuary2005andJanuary2006Hospital,Beijing100853.China;

6、MATERIALS:Tiscrewimplants(diameter2mm,length10mm,andpitch04mm)withoutthepartthatwentthroughgumwereDepartmentofoferedbyNonferrousMetalAcademyinBaoii.China.ThenonabsorbabIeTimembranes(2cmx2cm)wereoferedbyPrOsth0dOnticsZhongbangBiomaterialLimitedCompanyinXi’a

7、n,China,ThenHACmaterialsweregiftedbyprofessorCuiFu-zhaifromMaterialStomatologyHospital,F(xiàn)ourthScienceandEngineeringDepartmentofTsinghuaUniversityandfabricatedinto05mmx0.5mmx05mmsmallblocks.rhBMP2MilitaryMedicalwasoferedbytheAcademyofMilitaryMedicaISciencesi

8、nBeijing.China.rhBMP一2wasdissolvedwithhydrochloriccarbamidineUniversityofChinesePLAXi’anandthennHACwasimmersedinitVacuumizationfreeze.drying.a(chǎn)ndEkibondegermationwerefoIlowedEachgramofnHAC710032ShaanxIcompound

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