46例心臟瓣膜病合并冠心病同期手術(shù)的臨床療效分析

46例心臟瓣膜病合并冠心病同期手術(shù)的臨床療效分析

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1、授予單位代碼10089學(xué)號(hào)或申請(qǐng)?zhí)?0153242中國(guó)圖書分類號(hào)R541.4+R542.5HebeiMedicalUniversity碩士學(xué)位論文專業(yè)學(xué)位46例心臟瓣膜病合并冠心病同期手術(shù)的臨床療效分析研究生:張國(guó)利導(dǎo)師:陳子英教授專業(yè):外科學(xué)二級(jí)學(xué)院:河北醫(yī)科大學(xué)第二醫(yī)院2018年3月目錄中文摘要························································································1英文摘要································

2、························································2英文縮寫························································································4研究論文46例心臟瓣膜病合并冠心病同期手術(shù)的臨床療效分析前言························································································5材料與方法·

3、···········································································5結(jié)果······················································································7附表······················································································8討論···················

4、···································································11結(jié)論······················································································17參考文獻(xiàn)··············································································17綜述心臟瓣膜病合并冠心病同期手術(shù)的圍手術(shù)期處理·········

5、···················21致謝······························································································33個(gè)人簡(jiǎn)歷·······················································································34中文摘要46例心臟瓣膜病合并冠心病同期手術(shù)的臨床療效分析摘要目的:探討心臟瓣膜病合并冠心病同期手術(shù)治療的臨床效果,總結(jié)臨床經(jīng)驗(yàn)

6、。方法:回顧性分析2016年1月-2017年12月在我院心臟外科同期行心臟瓣膜病合并冠心病手術(shù)治療的患者共46例,期間行單純冠狀動(dòng)脈旁路移植術(shù)的患者共858例(死亡率為1%)。其中男性患者28例(60.8%),女性患者18(39.2%)例;平均年齡(59.4±7.3)歲;平均住院天數(shù)(30.7±9.0)天;體外循環(huán)時(shí)間(159.7±50.1)min;主動(dòng)脈的阻斷時(shí)間為(93.6±35.1)min;輔助循環(huán)時(shí)間(56.0±25.3)min;重癥監(jiān)護(hù)室時(shí)間(3.8±2.4)天;呼吸機(jī)輔助時(shí)間(1.8±1.3)天;通過觀察患者的臨床資料,比較術(shù)前、術(shù)

7、中、術(shù)后相關(guān)指標(biāo)變化及術(shù)后并發(fā)癥發(fā)生情況。結(jié)果:通過對(duì)本組患者術(shù)前和術(shù)后1周超聲心動(dòng)圖數(shù)據(jù)的收集,歸納,總結(jié),進(jìn)行統(tǒng)計(jì)學(xué)分析。左心室射血分?jǐn)?shù)(LVEF,leftventricularejectionfraction)與術(shù)前相比無(wú)統(tǒng)計(jì)學(xué)意義,左心室舒張末期內(nèi)徑(LVEDD,leftventricularend-diastolicdimension)與術(shù)前相比,有較好的改善,存在差異性,具有統(tǒng)計(jì)學(xué)意義(P<0.05)。術(shù)后出現(xiàn)并發(fā)癥共10例,其中肺部感染有4例,切口愈合不良有1例,神經(jīng)系統(tǒng)并發(fā)癥有1例,惡性心律失常2例,多器官功能衰竭1例,低心排綜

8、合征1例。本組死亡患者4例,死亡率為8.6%。結(jié)論:1.心臟瓣膜病合并冠心病,病情較復(fù)雜,是一種高危疾病。2.心臟瓣膜病合并冠心病同期手術(shù)治療,與單一

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