資源描述:
《摻釹釔鋁石榴石激光對(duì)小鼠移植瘤轉(zhuǎn)移的影響論文》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在工程資料-天天文庫(kù)。
1、摻釹釔鋁石榴石激光對(duì)小鼠移植瘤轉(zhuǎn)移的影響論文.freel-2,照射后第8日觀察腫瘤的生長(zhǎng)及肺轉(zhuǎn)移情況.結(jié)果不同方式激光照射組的腫瘤肺轉(zhuǎn)移程度明顯低于對(duì)照組(P0.01),封閉照射組腫瘤生長(zhǎng)慢于對(duì)照組(P0.01).結(jié)論不同方式的Nd-YAG激光治療可減少小鼠腫瘤肺轉(zhuǎn)移,提示Nd-YAG激光除體腔應(yīng)用外.freelouse;neoplasmmetastasisAbstract:AIMTostudytheeffectsofdifferentmannersofirradiationofNd-YAGlaseronmetastasisoftransplantedt
2、u-morinmice.METHODSNiy-ninemiceannersofNd-YAGlaser-2.Ontheeighthday,metastasisofthetransplantedtumortothelungetastasisoftrans-plantedtumorinmiceinthreelasergroupsshoorinsealingirradiationgroupgreorMetastasisinmicecanbeinducedbydifferentmannersofirradiationofNd-YAGlaser.Itsuggests
3、thatNd-YAGlasercanbeusedinen-doscope,decreasingthepossibilityoftumormetastasisinbinationium-yttriumalu-minumgar,Nd-YAG),波長(zhǎng)1.06μm,是近紅外激光,可經(jīng)石英光導(dǎo)纖維傳輸,水和血紅蛋白對(duì)其吸收較少,作用較深,是體腔腫瘤治療中較為理想的激光光源[1],已較廣泛用于體表及體腔腫瘤的治療[2,3].在惡性腫瘤的臨床治療中,盡管治療手段不斷完善,但仍有不少患者死于腫瘤轉(zhuǎn)移.如何在治療中抑制腫瘤轉(zhuǎn)移,提高療效,是人們關(guān)注的問(wèn)題之一.其他種類激光
4、對(duì)淋巴回流及腫瘤轉(zhuǎn)移影響的結(jié)論不一[4,5].我們用不同的Nd-YAG激光照射方式治療小鼠移植瘤,比較其治療效果及對(duì)腫瘤轉(zhuǎn)移的影響.1材料和方法1.1光源系統(tǒng)武漢產(chǎn)Nd-YAG激光器,輸出功率0~70E,A,LeonardPF.Anesthesiaforneo-dymium-YAG(Nd-YAG)laserresectionofmajorairors[J].Anesthesiology,1984;60(3):230-232.[2]PonecRJ,KimmeyMB.Endoscopictherapyofesophagealcan-cer[J].SurgCl
5、inNorthAm,1997;77(5):1197-1217.[3]GardnerA,HesteredicineInstitute,Acade-myofMedicalSciencesofChina.Experimentalstudyonim-plantableprosquamouscellcarcinomaofstomachofmouse[J].ZhonghuaZhongliuZazhi(ChinJOncol),1980;2(3):161-163.[7]GaoJ,QianSS,LiBG.Experimentalstudyonmetastasisoftu-
6、mourtreatedbyHpDbinetolaser[J].ZhonghuaZhongliuZazhi(ChinJOncol),1986;8(4):256-258.[8]LeiJY.Metastasisofmalignanttumour[J].GuomermannI,SternJ,F(xiàn)rankF.InterceptionoflyphaticdrainagebyNd:YAGlaserirradiationinraturinarybladder[J].LasersSurgMed,1984;4(2):167-172.[10]ShanghaiNeoplasmHo
7、spital.Zhongliudefangzhi(Thepreven-tionoftumour)[M].2nded.Shanghai:ShanghaiKexueJishuChubanshe(ShanghaiTechnologyPublishingHouse),1997:65.