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《血脂異?;颊遠(yuǎn)dl-c、甲狀腺激素與冠心病的相關(guān)性分析》由會員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫。
1、血脂異常患者HDL?C、甲狀腺激素與冠心病的相關(guān)性分析葉麗麗,阮云軍(廣州軍區(qū)總醫(yī)院心血管內(nèi)科,廣東廣州510010)摘要:【目的】研究長期規(guī)范降脂治療的血脂異常人群高密度脂蛋白膽固醇(HDL?C)、促甲狀腺素(TSH)、游離三碘甲狀腺原氨酸(FT3)、游離甲狀腺素(FT4)水平并分析HDL?C、TSH、FT3、FT4與冠心病的相關(guān)性?!痉椒ā渴占?014年4月至2017年04月于廣州軍區(qū)總醫(yī)院心血管內(nèi)科住院經(jīng)冠狀動脈造影明確診斷為冠心病的血脂界?;颊吖?52例,另外收集同期我院心內(nèi)科住院排除了冠心病的血脂異常
2、人群105例。入院后分別收集兩組血清樣本行血脂水平和甲狀腺功能檢測?!窘Y(jié)果】冠心病組和對照組的HDL?C、TSH、FT3、FT4水平比較,HDL?C、FT3差異具有統(tǒng)計(jì)學(xué)意義(PvO.05);冠心病組及對照組TSH、FT3、FT4與HDL-C均無明顯相關(guān)(P>0.05);在對照組中,TSH、FT4與TG、TSH與TC有相關(guān)性,差異具有統(tǒng)計(jì)學(xué)意義(PV0.05)。【結(jié)論】長期規(guī)范降脂治療的冠心病患者HDL?C、FT3水平均下降,提示HDL-C可能可以減少、延緩冠心病的發(fā)生和發(fā)展,而甲減可能是冠心病的危險因素之一。
3、關(guān)鍵詞:冠心??;血脂異常;HDL?C;甲狀腺激素CorrelationAnalysisbetweenHDL-C>ThyroidHormoneLevelsandCoronaryHeartDiseaseinPatientswithDyslipidemiaYeLili,RuanYunjun(DepartmentofCardiology,MilitaryGeneralHospitalofGuangzhouCommand,Guangzhou510010,China)Abstract:[Objective]Theaimof
4、thisstudywastoinvestigatethelevelofHDL-C、TSH>FT3、FT4andHDL-Cinpatientswithdyslipidemiawhohavelong-termlipid-loweringtherapyandthecorrelationbetweenHDL-C、TSH、FT3、FT4andcoronaryheartdisease.【Methods]Wecollected152casesofdyslipidemiapatientdiagnosedwithcoronary
5、arterydiseasebycoronaryangiographyinMilitaryGeneralHospitalofGuangzhouCommandfrom2014-04to2017-04andcollected105casesofdyslipidemiapatientdiagnosedwithoutcoronaryarterydisease.Theserumsamplesintwogroupswerecollectedtodetecttheserumlipidlevelsandthyroidfuncti
6、on.【Results】Comparedwiththecontrolgroup,thedifferenceofHDL-CandFT3fromcoronaryheartdiseasegrouptwasstatisticallysignificant(P<0.05)?However,inpatientswithCHDandcontrolgroup,therewasnosignificantcoiTelation(P>0.05)betweenTSH>FT3、FT4andHDL-C.Incontrolgroup,TSH
7、^FT4correlatedwithTG、TSHcorrelatedwithTC,thedifferencewasstatisticallysignificant/P<0.05)?【Conclusions]Inpatientswithdyslipidemiaandcoronaryheartdisease,thelevelofHDL-CandFT3decreased,whichpointoutthatHDL-Cmaydeferthedevelopmentofcoronaryheartdiseaseandhypot
8、hyroidismisoneoftheriskfactor.Keywords:coronaryheartdisease;dyslipidemia;highdensitylipoprotein-cholestrol:thyroidhormone冠心病(CHD)的發(fā)生、發(fā)展與年齡、吸煙、高血壓、糖尿病、血脂異常等因素密切相關(guān),而在這其中,血脂異常被認(rèn)為是獨(dú)立而重要的危險因l41-2Jo但有