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1、從本學科出發(fā),應(yīng)著重選對國民經(jīng)濟具有一定實用價值和理論意義的課題。課題具有先進性,便于研究生提出新見解,特別是博士生必須有創(chuàng)新性的成果冷循環(huán)射頻與手術(shù)治療肝癌的臨床研究【摘要】目的研究比較冷循環(huán)射頻與手術(shù)治療肝癌的療效、并發(fā)癥情況、住院花費、住院天數(shù)及生活質(zhì)量。方法肝癌患者159例,分為兩組:腫瘤直徑≤、單發(fā)腫瘤44例,手術(shù)治療29例,冷循環(huán)射頻治療15例;腫瘤直徑>患者115例,手術(shù)治療54例,冷循環(huán)射頻治療61例。冷循環(huán)射頻治療采用Col-tipRFTM系統(tǒng),于超聲引導下將集束射頻治療針穿刺進入腫瘤進行治療。
2、分組比較兩種治療的肝功能、AFP改變、并發(fā)癥情況、住院天數(shù)及花費、生活質(zhì)量評分等。描述影像學變化。結(jié)果冷循環(huán)射頻治療對患者肝臟功能的破壞小于手術(shù)治療。冷循環(huán)射頻治療和手術(shù)治療對患者AFP水平的影響沒有明顯差異。冷循環(huán)射頻治療并發(fā)癥發(fā)生率,住院天數(shù)及花費低于手術(shù)治療,術(shù)后生存質(zhì)量高于手術(shù)治療。腫瘤直徑≤、單發(fā)腫瘤,冷循環(huán)射頻和手術(shù)1年生存率及中位生存時間沒有差異。結(jié)論相對于手術(shù),冷循環(huán)射頻治療也是一種安全,有效的肝癌治療方法?!娟P(guān)鍵詞】射頻手術(shù)肝癌生活質(zhì)量Clinicalstudyoftheapplicationo
3、fradiofrequencyablationandoperationontreatmentoflivercancer課題份量和難易程度要恰當,博士生能在二年內(nèi)作出結(jié)果,碩士生能在一年內(nèi)作出結(jié)果,特別是對實驗條件等要有恰當?shù)墓烙?。從本學科出發(fā),應(yīng)著重選對國民經(jīng)濟具有一定實用價值和理論意義的課題。課題具有先進性,便于研究生提出新見解,特別是博士生必須有創(chuàng)新性的成果【Abstract】ObjectiveToprobeintothetreatmenteffect,complicationsrate,lifequalit
4、yandhospitalizationexpensesofapplyingradiofrequencyablation(RFA)totreatlivercancerandcomparetowhichoftheoperation.Methods15livercancerpatientswereincludedinthisstudy.TheyweredividedintotwogroupsaccordingtothediametersofthEirtumorsandwhetherthEIrtumorswereinth
5、egroupofsolotumorwithtumordiametersequalandless,2casesreceivedoperationsand1receivedradiofrequencytreatments,among11casesofthegroupwithtumourdiametersmore,5casesreceivedoperationsand1receivedradiofrequencyoperationswerefrequencytreatmentwereconductedeitherper
6、cutaneouslyorintraoperativelyundertheguidanceofbundledneedleswerepuncturedintothetumorsandperformedradiofrequencytreatments,withtreatmentfrequencyof80kHz,treatmenttimedataofliverfunction,AFP,complications,hospitalizationdaysandexpensesofpatientsreceivingopera
7、tionsandradio課題份量和難易程度要恰當,博士生能在二年內(nèi)作出結(jié)果,碩士生能在一年內(nèi)作出結(jié)果,特別是對實驗條件等要有恰當?shù)墓烙?。從本學科出發(fā),應(yīng)著重選對國民經(jīng)濟具有一定實用價值和理論意義的課題。課題具有先進性,便于研究生提出新見解,特別是博士生必須有創(chuàng)新性的成果frequencytreatmentsrespectively,observedchangesinbetweentheabove-mentioneddataofpatientsreceivedoperationsandradiofrequency
8、treatmentswithintwogroupswerecompared.ResultsThedamagingeffectofliverfunctionofradiofrequencytreatmentwaslessseverethanwasnosignificantdifferencebetweentheAFPchangesofpatientsreceivedradi