資源描述：
《ngal在單側(cè)輸尿管結(jié)扎大鼠腎臟的表達(dá)與促肝細(xì)胞生長(zhǎng)素對(duì)其影響》由會(huì)員上傳分享，免費(fèi)在線(xiàn)閱讀，更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫(kù)。
1、英文摘要obstmction(UUO)ratkidney，andt11ecorrelationbetweenHGF，NGALandE．cadherein(E．cad)under也enerventionofexogenousHGF’and也enexploret11emechaJlismbetweenHGF’NGALandtheprocessof‘cdamage．repan6brosis’’，t11usprovidenewideasforthetreatmentofrenalfibrosis．Method：72cleanlevelhealt}lymaleSDrats，bodywei出
2、200士20g，wererandomlydividedintothreegroups：(1)shamoperation鏟oup(sh鋤group)：onlysepaI．a(chǎn)tetheleRureter，noligatedorcut，In仃aperitonealinjection(IP)ofsalinedaily；(2)吼ilateralureteral0bstmction一0perationgroup(UUOgroup)：meleRureterwasligatedandcut，I腑aperitonealinjectionofsalinedaily；(3)h印atoc”egrowth
3、promotingf-acto—nterventiongroupQHGFgroup)：me1eRureterwasligatedandcut，pHGFO．5m刪daybyI．Pdaily．RatsineaChgroupreceiVedintr印eritoneal塒ection舶mldaybeforemeoperationurltilthe14mpostoperative￡lay，inwhichtheVolumeofsalineinSh鋤groupaIldUUOgroupwaSequaltothepHGF伊oup．Duringtheexperimentratswereprovide
4、dwith仔eefoodandwater．6ratswererandomlyselectedoutofeachgroupInthe1st，4th，7th，14thdaysaRertheoperation．TheleRl(idneyswereharVestedandmadeintosections．RespeCtively，tllepatllologicalchangesofrenaltissuewithhematoxylineosin(HE)a11dMassonstainingwereobsen，edunderthe1ightmicroscope；NGAL，E．cadandHGF
5、expressionwereexaminedbyImmunohistochemicalmethod．7IheresultswereanalyzedusingmeimageanalysissystemIPP(Image—ProPlus)forsemi．quamitatiVeanalysis．Allthedatawereexpressedasmean士standarddeviation，singlef．a(chǎn)ctoranalysisofVariancewasused鋤ongmethreegroups，twoiIldependents鋤plest-testbetweentwo鏟oups，a
6、ndnon．parametrictestsforthedatawhichdidnotmeetthenomalit)，andhomogenei鈔ofv撕ance．S洲Stic出anaJysisso腳areSPSSl7．Ow2Lsusedfordatastatistics，witllP7、ubulointerstitialareaaIldthecontentofrenalinterstitialc011agenfiber5英文摘要increased鱸aduallywithureteralobstmctionprolonged，whichsuggestedanincreasingleVelofrenalinterStitialfibrosis．ComparedwimUUO鱸oup，thehistopathologicalchangeswerea11eVi2噸edin
