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1、超聲造影引導(dǎo)下經(jīng)皮肺外周型病變穿刺活檢的探討中南大學(xué)湘雅二醫(yī)院超聲科湖南長(zhǎng)沙410011【摘要】目的:探討超聲造影引導(dǎo)下肺外周型病變經(jīng)皮穿刺活檢病理診斷陽(yáng)性率的成功率以及影響因素。方法:回顧性研究82例肺外周型病變患者的穿刺病理結(jié)果,將其分為造影組(30例)和非造影組(52例),比較兩組患者超聲引導(dǎo)下穿刺活檢的成功率,并對(duì)其影響因素進(jìn)行分析。結(jié)果:經(jīng)皮肺外周型病變82例,二維超聲引導(dǎo)下穿刺病理診斷陽(yáng)性率為86.5%(45/52),超聲造影引導(dǎo)下穿刺病理診斷陽(yáng)性率為96.7%(29/30);兩組病灶的平均前后徑分別為:造影組(3.35±0.14)cm和非造影組(2.43&plus
2、mn;0.26)cm,兩者比較差異有統(tǒng)計(jì)學(xué)意義(p=0.012)o非造影組病灶前后徑為1.0?2.0cm、2.1?3.0cm、3.1?5.0cm和大于5.0cm的病理診斷陽(yáng)性率分別為:78.5%、88.9%、85.7%和85.7%。造影組病灶前后徑為1.0?2.0cm>2.1?3.0cm、3.1?5.0cm和大于5.0cm的病理診斷陽(yáng)性率分別為:100%、100%、90%和100%。結(jié)論:超聲可視的病灶大小是影響超聲引導(dǎo)下經(jīng)皮肺外周型病變穿刺活檢病理診斷陽(yáng)性率的重要因素,超聲造影引導(dǎo)下穿刺活檢可避開壞死組織,增加活檢的成功率?!娟P(guān)鍵詞】超聲造影;穿刺活檢;肺外周型病變AbstractObje
3、ctive:ToanalysisandSummarizeclinicalexperienceinContrastenhancedultrasound-guidedpercutaneouspuncturebiopsyofperipheralpulmonarylesions.Methods:Retrospectiveanalysisof82patientswithperipheralpulmonarylesionswhounderwentultrasound—guidedpercutaneousIungbiopsy,WeclassifiedthecasesintotwogroupContrast
4、enhancedultrasoundgroup(30cases)andNoncontrastenhaneedultrasoundgroup(52cases)toevaluatethefactorsaffectingPositiverateofpathologicaldiagnosisInultrasound-guidedpercutaneouspuncturebiopsyofthelung.Rsults:ThepositiverateofpathologicaldiagnosisWas86.5%(45/52)inNoncontrastenhancedultrasoundgroup,96.7%
5、(29/30)inContrastenhancedultrasoundgroup.Lesionsizewasasignificantfactorcontributingtopositiverateofpathologicaldiagnosis(p=0.012).MeanAnteroposteriordiameteroflesions(±SD)inthetwogroupswere3.35±0.14cm(Contrastenhaneedultrasoundgroup)and2.43±0.26cm(Noncontrastenhaneedultrasound
6、group).Forlesions1.0-2.0cm>2.1-3.0cm>3.1-5.0cmand>5.0cminanteroposteriordiameter,thepositiverateofpathologicaldiagnosiswas78.5%、88.9%.92.3%and85.7%inNoncontrastenhancedultrasoundgroup,andwas100%、100%、100%、90%和100%incontrastenhancedultrasoundgroup.Conclusion:Lesionsizewasadeterminingfactorinposit
7、iverateofpathologicaldiagnosis.Thepositiverateofpathologicaldiagnosisdecreasedinproportiontothedecreaseinthelesionanteroposteriordiameter.However,puncturebiopsyguidedbycontrast-enhancedultrasoundcanincrease