資源描述:
《蝸神經(jīng)管狹窄與蝸神經(jīng)發(fā)育相關(guān)性-研究》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在行業(yè)資料-天天文庫(kù)。
1、山東大學(xué)碩士學(xué)位論文1、41例患兒中7例(14耳)出現(xiàn)內(nèi)耳畸形即異常組,14耳中6耳CNC>0.18mm,蝸神經(jīng)均發(fā)育正常;2耳CNC0.18mm---0.15mm,蝸神經(jīng)均正常;6]豐CNC<0.15mm,其中2耳蝸神經(jīng)正常。34例(62耳)正常組中43耳CNC>0.18mm,41耳蝸神經(jīng)正常;1l耳CNCl.8mm---1.5mm,9耳蝸神經(jīng)正常;8:E[CNC<0.15mm,均存在蝸神經(jīng)發(fā)育不良。將三組數(shù)據(jù)分別進(jìn)行四格表確切概率法統(tǒng)計(jì)處理,分別得出p=1.0,p=1.0,p=0.165,均>O.05,不存在統(tǒng)計(jì)學(xué)差異。2、合并正常及異常組,41例(76耳)中49耳
2、CNC>0.18mE,其中2耳蝸神經(jīng)發(fā)育不良:13耳CNCl.8mm-~1.5mm,2耳蝸神經(jīng)發(fā)育不良;14耳CNC<0.15mm,12耳蝸神經(jīng)發(fā)育不良。將所得數(shù)據(jù)通過(guò)SPSS軟件進(jìn)行spearman相關(guān)性分析,得出相關(guān)系數(shù)r=0.658,各組蝸神經(jīng)發(fā)育不良分別占4.1%、15.4%、85.7%。結(jié)論1、蝸神經(jīng)管一定情況下,非耳蝸性內(nèi)耳畸形與蝸神經(jīng)發(fā)育無(wú)明顯相關(guān)性;2、蝸神經(jīng)管狹窄與蝸神經(jīng)發(fā)育呈中度正相關(guān)性,蝸神經(jīng)管越窄,提示合并蝸神經(jīng)發(fā)育不良準(zhǔn)確性越高,CNC<0.15mm,強(qiáng)烈提示蝸神經(jīng)發(fā)育不良的存在。3、蝸神經(jīng)管在各個(gè)管徑水平下均見(jiàn)到正常及發(fā)育不良的蝸神經(jīng),因此在
3、人工耳蝸植入術(shù)前,CT、MRI均是不可缺少的檢查手段。意義蝸神經(jīng)發(fā)育不良是由于先天發(fā)育異常或后天退行性變引起的蝸神經(jīng)形態(tài)、功能的改變,蝸神經(jīng)作為聽(tīng)覺(jué)通路的重要通道,患者常伴嚴(yán)重的感音性耳聾,因此蝸神經(jīng)發(fā)育不良會(huì)給患者帶來(lái)嚴(yán)重后果。目前對(duì)蝸神經(jīng)發(fā)育不良的治療效果并不肯定,以前認(rèn)為蝸神經(jīng)發(fā)育不良是人工耳蝸植入的絕對(duì)禁忌癥,但隨著日益增多的人工耳蝸手術(shù),部分患者取得良好的效果,但目前多數(shù)學(xué)者認(rèn)為蝸神經(jīng)發(fā)育不良手術(shù)效果不佳,有學(xué)者認(rèn)為這部分病人可以選擇聽(tīng)性腦干植入(auditorybrainstemimplantsABI)n1。本研究通過(guò)分析蝸神經(jīng)管狹窄與蝸神經(jīng)發(fā)育相關(guān)性,論證
4、HRCT下蝸神經(jīng)管狹窄在診斷蝸神經(jīng)發(fā)育不良中的價(jià)值,不僅對(duì)以往的研究進(jìn)行了補(bǔ)充,而且為HRCT在感音性耳聾的病因?qū)W診斷提出一新的分型,從而為臨床進(jìn)一步的診斷及治療提供依據(jù)。關(guān)鍵詞體層攝影術(shù),X線技術(shù);磁共振成像;蝸神經(jīng)管;蝸神經(jīng);2山東大學(xué)碩士學(xué)位論文———————————————————————————————————————————————————————一0bjetive:TherelationshipbetweenthecochlearnerveCanalstenosisandthecochlearnervePostgraduate:LiuWeiTutor:Sp
5、ecialty:WangTaoGongRuo-zhenImagingandNuclearMediciAbstractTheaimofthisstudyistoexploretherelationshipbetweencochlearnervecanal(CNC)stenosisandcochlearnerve(CN)byusingmulti-sliceCTandmagneticresonanceimaging(MRI)inchildrenwithsensorineuralhearingloss.Methods:Duringaperiodof16months,51chil
6、dren(102ears)withunilateralorbilateralsensorineuralhearingloss(SNHL)underwentbothHRCTandM剛imagingoftemporalbone.The51patientsisconsistedof3malesand18femaleswithameanageof4years(rangefrom9monthto10years).45patientswithbilateralsensorineuralhearingloss,6patientswithunilateralsensorineuralh
7、earingloss.41patients(82ears)withnormalinneracousticcanal(IAC)andcochlearexistencewerechoosedforthisstudy,Forallofthese,theCNCwereme齜edanddividedintothreegroupsaccordingtothediameterofCNConHRCT,a:>1.8mm,b:1.8mm~1.5mnl,c:<1.5mill,atthesametime,thepresenceofCNhypoplasiaorap