37.An S-type bypass can improve the hemodynamics in the bypassed arteries and suppress intimal hyperplasia along the host artery floor.pdf

37.An S-type bypass can improve the hemodynamics in the bypassed arteries and suppress intimal hyperplasia along the host artery floor.pdf

ID：34072167

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時間：2019-03-03

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1、ARTICLEINPRESSJournalofBiomechanics41(2008)2498–2505www.elsevier.com/locate/jbiomechwww.JBiomech.comAnS-typebypasscanimprovethehemodynamicsinthebypassedarteriesandsuppressintimalhyperplasiaalongthehostartery?oorabca,daYuboFan,ZaipinXu,WentaoJiang,XiaoyanDeng,KeW

2、ang,AnqiangSunaDepartmentofBioengineering,BeihangUniversity,37XueyuanRoad,HaidianDistrict,Beijing100083,ChinabDepartmentofVeterinaryMedicine,GuizhouUniversity,Guiyang,ChinacSichuanUniversity,Chengdu,ChinadTheFirstAf?liationHospital,DalianMedicalUniversity,Dalian,

3、ChinaAccepted11May2008AbstractThedevelopmentofdistalend-to-sideanastomoticintimalhyperplasia(IH)hasbeenattributedtothe?owdisturbanceandabnormalwallshearstress(WSS)distributionthere.Thegeometryofthebypasshasastrongin?uenceonthe?owpatternandWSSdistribution.Usingaca

4、ninemodelofend-to-sideanastomosis,a451S-typebypasswascomparedwith601,451and301conventionalbypassesinthetermofIHalongthehostartery?oor.Numericalblood?owsimulationswerealsocarriedouttocharacterizethe?owpatternsatthedistalpartsofthebypassedarteriesforthe4models.Ther

5、esultsshowedthattheaveragedintimathicknessesofthehostartery?oorsforthe4bypassmodelswere119.50710.30mm(601),65.5676.53mm(451),45.2675.99mm(301)and47.6474.85mm(S-type),respectively,vs.9.8171.88mminthecontrolgroup(withoutbypasssurgery).Comparedwiththecontrolgroup,ne

6、ointimathicknessinall4bypassmodelswassigni?cantlyincreased,buttheneointimathicknessofthe451S-typebypasswasapparentlymuchbetterthanits451conventionalcounterpart,andwasasgoodasthe301conventionalbypass.Thenumericalsimulationrevealedanapparentswirling?owpatternintheS

7、-typebypass,whichwasverydifferentthanthe?owpatternsinthe3conventionalbypassmodels.Thisswirling?owalteredtheoverall?owpatterninthedistalpartofthebypassedarteryandeliminatedthelowWSSzonealongthehostartery?oor.TheimprovementinthetermofIHfortheS-typebypassismostlikel

8、yduetothealterationoftheoverall?owpatternandWSSdistributionbythegeometricalcon?gurationoftheS-typebypass.r2008ElsevierLtd.Allrightsreserved.Keywords:S-typebypa

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