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1、中國實用眼科雜志2010年5月第28卷第5期ChinJIcl_Opbthalmol,May2010,Vol28,No.5·489·一—·論著:臨床研究·多焦視網(wǎng)膜電圖對鈍傷性睫狀體分離眼手術(shù)前后視功能的評價。裴文周南【摘要】目的應(yīng)用多焦視網(wǎng)膜電圖研究鈍傷性睫狀體分離眼手術(shù)前后各部位視網(wǎng)膜功能,探討睫狀體分離眼視功能損害機制,為治療及手術(shù)方法的選擇與改進,預(yù)后的評估提供參考。方法應(yīng)用VERISscienceTM4.2多焦電生理系統(tǒng)對43例鈍傷性睫狀體分離眼術(shù)前術(shù)后及對側(cè)眼進行mfERG檢測,以mfERG一階反應(yīng)N1波、P1波的振幅密度、潛時為分析指標(biāo)
2、,對不同視網(wǎng)膜區(qū)域包括6個離心度,中心凹、黃斑區(qū)、黃斑外區(qū)進行檢測。對視力與mfERG的關(guān)系進行分析。結(jié)果鈍傷性睫狀體分離組患眼手術(shù)前后的mfERG比較:N1、P1波振幅密度術(shù)后較術(shù)前明顯提高,術(shù)后潛時較術(shù)前縮短,在6個環(huán)差異均有統(tǒng)計學(xué)意義(P0.05),術(shù)前視力與術(shù)后mfERG存在等級相關(guān)(P
3、<0.05)。結(jié)論mfERG能對鈍傷性睫狀體分離眼視網(wǎng)膜功能進行定位定量測量?!娟P(guān)鍵詞】多焦視網(wǎng)膜電圖;鈍傷性睫狀體分離;視功能AssessmentofvisualfunctionwithMultifocalElectroretinograminpatientswithcyclodialysiscleftbeforeandaftersurgeryPEIWen,zHoUNan,TianjinEyeHospital,Tianjin300040,China【AbstractlObjeetiveInordertogiveaconvenientcriteri
4、ontoselectandimprovetheoperationskillsaswellasprovideausefulreferencetoprognosis,multifocalelectroretinalgram(mfERG)wastakentostudythevariousfunctionoftheretinaindiferentlocationsandthemechanismofthedamagetothevisualfunctionofthecyclodialysiscleftbeforeandaftersurgery.MethodsT
5、hemfERGof43cyclodialysisclefteyesbeforeandaftersurgeryandthefelloweyeswererecordedbyVERISEScienceTM4.2multifocalvisualevokedre—sponseimagingsystem.BasedonthefirstorderkernelofN1andP1waves,changesindifferentareaincludingthediferenteccentricities,centralfoveal,macularareaandextr
6、a.macularareawereinvestigated.ResultsThecomparisonofmfERGofcyclodialysisclefteyesbeforeandaftersurgeryshowedthattheamplitudeofP1andN1wavesincreasedinsixringsaftertheoperation.Thelatenciesalsoshortened.Thedifferencesinsixringswerestatisticallysignificant(P<0.01).Thecomparisonof
7、mfERGoftheaffectedeyesofcyclodialysisclefteyesaftersurgeryandthefelloweyes,thelatenciesofN1andP1waveinsixringsweresignificantlydelayed(P<0.01)andtheiramplitudesin1-6ringsmarkedlydecreasedinthegroupofcyclodialysisclefteyes(P8、dorientationaldetectionforthevisualfunctionoftheeyeswiththecy