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1、學校代碼：10600學號：101065學位類型：科學學位廣西中醫(yī)藥大學碩士學位論文血府逐瘀湯對大鼠體內(nèi)藥物代謝酶和抗氧化酶的影響研究研究生：樊星花導師：楊秀芬教授院系（部所）：藥學院專業(yè)：藥理學研究方向：生化藥理完成日期：2013年5月24日0目錄中英文縮略詞匯表···············································································1中文摘要························································
2、····································3英文摘要····························································································5引言·····························································································9正文········································
3、···················································10第一部分血府逐瘀湯水提物對大鼠肝臟藥物代謝酶活性的影響············101實驗材料和方法·············································································101.1實驗藥物和試劑··········································································101.2實驗
4、動物····················································································111.3主要儀器設(shè)備··············································································111.4實驗方法····················································································111.
5、4.1藥物煎煮方法···········································································121.4.2動物給藥方法···········································································121.4.3微粒體的制備···········································································121.4.4血府逐瘀湯
6、水提物對正常大鼠肝臟藥物代謝酶活性的影響············131.4.4.1氨基比林-N-脫甲基酶(CYP3A)活性的測定································131.4.4.2苯胺-4-羥化酶(CYP2E1)活性的測定··········································131.4.4.3細胞色素b5的測定·································································141.4.4.4NADPH-細胞色素C還
7、原酶的測定·········································141.4.4.5谷胱甘肽-S-轉(zhuǎn)移酶(GST)活性的測定········································141.4.4.6葡萄糖醛酸-轉(zhuǎn)移酶(UDPG-T)活性的測定··································141.4.5統(tǒng)計學處理···············································································1
8、52實驗結(jié)果·······················································································152
