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1、ChengduUniversityofTraditionalChineseMedicine(藥學院)二0一八屆碩士研究生學位論文通絡(luò)醒腦泡騰片活性成分P-15通過自噬-溶酶體途徑抗AD的機制研究StudyonthemechanismofprotectionofP-15,anactivecomponentofTongluoXingnaoeffervescenttablets,inAlzheimer’disseasethroughautophagy-lysosomepathway研究生姓名:孟詩指導教師:徐世軍教授學科專業(yè):藥理學二0一八年五月成都中醫(yī)藥大學2018屆碩士畢業(yè)生論文學位論文通絡(luò)醒
2、腦泡騰片活性成分P-15通過自噬-溶酶體途徑抗AD的機制研究StudyonthemechanismofprotectionofP-15,anactivecomponentofTongluoXingnaoeffervescenttablets,inAlzheimer’disseasethroughautophagy-lysosomepathway孟詩指導教師姓名:徐世軍(教授)申請學位級別:碩士專業(yè)名稱:藥理學論文提交時間:2018年4月論文答辯時間:2018年5月二○一八年五月II成都中醫(yī)藥大學2018屆碩士畢業(yè)生論文目錄摘要.................................
3、.....................................................................................................................IABSTRACT...................................................................................................................................VIII前言....................................
4、.................................................................................................................1英文縮略詞表.....................................................................................................................................8實驗研究.........................................
5、....................................................................................................9第一部分基于AD細胞模型的通絡(luò)醒腦泡騰片活性成分篩選研究..........................................91.實驗材料.........................................................................................................................
6、.........92.實驗方法................................................................................................................................103.實驗結(jié)果................................................................................................................................134.小結(jié).............
7、...........................................................................................................................25第二部分P-15對Aβ25-35誘導的SH-SY5Y細胞損傷的自噬-溶酶體途徑的調(diào)控作用及機制研究................................