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1、OrganTransplantationOrganTransplantationQiQiZhangM.D&ZhangM.D&Ph.DPh.DEmail:kee_kee@126.comLiverTransplantationCenteroftheThirdAffiliatedHospital,SYSUOrgantransplantation--Mt.EverestofmedicalscienceFemale,49yFemale,49yBBeautifuleautifulRRichichSingleandSadSingleandSadP
2、olycysticliverandPolycysticliverandkidneydiseasekidneydiseaseHermotherandHermotherandeldersisterbotheldersisterbothdiedofthesamediedofthesamedisease.disease.OnhemodialysisOnhemodialysisComparedwithnormalliver&kidneyComparedwithnormalliver&kidneyNormalPolycysticliverand
3、kidneyRemovedorgansandgraftsRemovedorgansandgraftsIntensivecareunit(ICU)anddischargeIntensivecareunit(ICU)anddischargeFollowupFollowupHeryoungersistersufferedHeryoungersistersufferedfromthesamedisease.fromthesamedisease.Historyrepeateditself.Historyrepeateditself.Organ
4、TransplantationOrganTransplantationOverviewoftransplantationOverviewoftransplantationTransplantationimmunityandpreventionTransplantationimmunityandpreventionProcurementandpreservationofgraftsProcurementandpreservationofgraftsOrgantransplantationOrgantransplantationHist
5、oryoftransplantationHistoryoftransplantationFantasystageFantasystageEmpiricalstudystageEmpiricalstudystageClinicalearlystageClinicalearlystageClinicaldevelopingstageClinicaldevelopingstageFantasystageFantasystage2000yearsago,Pianque“剖胸探心，，易而治之，易而治之”EmpiricalstudystageE
6、mpiricalstudystageInventedanewvascularAnastomosisAlexisCarrel,NobelPrizewinnerin1912forMedicineorphysiologyClinicalearlystageClinicalearlystageJosephMurrayKidneytransplantationbetweenidenticaltwins,in1954Kidneytransplantationbetweenfraternaltwins,in1959Cadaverickidneyt
7、ransplantation,in1962NobelPrizewinnerin1990ClinicaldevelopingstageClinicaldevelopingstageYearOperatorTransplants1963HardyLung1963StarzlLiver1964HardyHeart(Xenograft)1966Lillehei&KellyPancrea1966KellySPK1968DetterlingSmallintestine1967BarnardHeart(Allograft)1967Lacy,Kos
8、tianovskyIslettransplantation1981ReitzHeart/Lung1983Williams,StarzlMulti-organtransplants……1978CyclosporineFacialFaci
