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《Id2在成年大鼠腦中的表達(dá)及其影響SVZa神經(jīng)干細(xì)胞發(fā)育分化的初步研究》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫。
1、第三軍醫(yī)大學(xué)碩士學(xué)位論文常用英文縮寫一覽表縮寫英文全稱中文名稱APSAmmoniumpersulfate過硫酸胺bFGFBasicfibroblastgrowthfactor堿性成纖維細(xì)胞生長因子bHU{Basicheli】【-loop-helix堿性螺旋.環(huán).螺旋結(jié)構(gòu)域BrdUBromodeoxyuridine溴脫氧尿嘧啶尿苷CNSCcaatralnervoussystem中樞神經(jīng)系統(tǒng)DAB3.3’-diaminobenzidlne3。3’.二氨基聯(lián)苯胺DEPCDiethylpyrocarbonate焦碳酸二乙脂DAIEMDulb
2、ecco’smodifiedeaglemedium改良的基礎(chǔ)培養(yǎng)基開rCFluoresceinisothiaeyanate異硫氰酸熒光素GEAPGlialfibrfltm'yacidicprotein膠質(zhì)纖維酸性蛋白Id2InhibitorofDNAbinding一2DNA結(jié)合抑制因子2LvLateralventricle側(cè)腦室mRNAMessageRNA信使RNANestinNeuroepitheliastemcellprotein神經(jīng)上皮干細(xì)胞蛋白NFNeurofilament神經(jīng)絲蛋白NSCsNeuralstemcells神經(jīng)
3、干細(xì)胞oBOlfactorybulb嗅球oDOpticaldensity光密度值PA(mPolyaerylamidegelelectrophoresis聚丙烯酰胺凝膠電泳PBSPhosphatebufferedsaline磷酸鹽緩沖液RMSRostralmigratoryslream嘴側(cè)遷移流第三軍醫(yī)大學(xué)碩士學(xué)位論文rpmm二PCRSAGESVZa咖DT3THRollperminuteReversetranscription—polymerasechainreactionSerialanalysisgeneexpressionAnt
4、eriorsubvenlricularzoneN'N,N’,NiTetramethyl-ethylenediamineTriiodothyronineTyrosinehydroxylase2每分鐘轉(zhuǎn)數(shù)逆轉(zhuǎn)錄聚合酶鏈?zhǔn)椒磻?yīng)基因表達(dá)連續(xù)分析法室管膜前下區(qū)N,N,N’,N’一四甲基乙二胺三碘甲腺原氨酸酪氨酸羥化酶第三軍醫(yī)大學(xué)碩士學(xué)位論文TheExpressionofId2inAdultRatBrainanditsEffectsontheDevelopmentandDifferentiationofSVZaNeuralStemCellsAb
5、stractItisbelievedthattheanteriorsubvenlricularzone(SVZa)andhippocampusarethemostnumerousaiP紐sofneuralstemcells(NSCs)inadultmammalbrain.neSVZaNSCscontinuouslymigratefromSVZatoolfactorybulb(OB)bythemammal’Swholelife’andformtheroslralmigratorystream(gMS).SotheSVZaNSCsare
6、therenewingresourceofOBintemeurons.BesideshavingthegeneralcharacteristicsofNSCs,theSVZaNSCshavetheiruniquefeaturesthemselves..nleSVZaNSCscankeepundifferentiatedallalongin捌MS.AfterarrivingatthecenterofOB。theNSCsthenmigratearoundanddifferentiateintoneuronsandneuralgliace
7、ils.髓edifferentiationofNSCsareaffectednotonlybyinheritfactorssuchasthyroidhormonereceptorsinthecells,butalsobyextracellularsignalssuchasmitogenicfactors(EGF),thyroidhormone(Ts),glucocorticoids,retinoicacid(RA),serum.黜kindofthemechanismitisthatwhytheSVZaNSCskeepundiffer
8、entiatedallalonginRMSisstillunclearnow.弧ecolleaguesinOurlabhadobservedthattranscriptionfactorssuchasBMP2,Mashl,Pax6,W