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1、實(shí)驗(yàn)動(dòng)物的麻醉劑量表表1.小鼠(mouse)麻醉劑量表藥物劑量/BW途徑麻醉前給藥Atropin0.002-0.005mg/100gIV,IM,SC0.12mg/100gIP鎮(zhèn)靜劑Acepromazine0.075mg/100gIMDiazepam0.5mg/100gIPKetamine2.0mg/100gIM注射麻醉劑Ketamine2.2-4.4mg/100gIM10mg/100gIP2.5mg/100gIVPentobarbital1.5mg/100gIV6.0mg/100gIPThiopental2.5mg/100
2、gIV5.0mg/100gIPThiamylal2.5-5.0mg/100gIV混合注射麻醉劑Ketamine+Xylazine8.7mg+1.3mg/100gIM,IPKetamine+Acetylpromazine2.2-4.4mg+0.075mg/100gIM吸入麻醉劑CarbondioxideInduction:10-15secondsHalothaneInduction:1-3%Maintenance:0.5-1.5%Isoflurane1-4%toeffectMethoxyfluraneInduction:2-
3、4%Maintenance:0.5-1.5%止痛劑Meperidine2.0mg/100gIM,SC0.4mg/100gIPButorphanol0.1-0.5mg/100gSC,IMPentacozine1.0mg/100gSC,IM,IVNalbuphine0.5mg/100bSC,IMBuprenorphine0.2mg/100gq12hSC0.2mg/100gq6-8hIP不推薦使用的藥物ChloroformEtherCarbontetrachlorideChlorpromazineTrichloroethylen
4、eTribromoethanolIM:肌肉注射IV:靜脈注射SC:皮下注射IP:腹腔注射Inhalation:吸入Reference:1.實(shí)驗(yàn)動(dòng)物管理與使用指南。(中華實(shí)驗(yàn)動(dòng)物學(xué)會(huì)出版2005)表2.大鼠(Rat)麻醉劑量表藥物劑量途徑麻醉前給藥Atropin0.02-0.05mg/kgIV,IM,SC鎮(zhèn)靜劑Acepromazine5mg/kgIM,SCDiazepam2.5mg/kgIPXylazine13mg/kgIMKetamine22mg/kgIM20mg/kgIP注射麻醉劑Ketamine44mg/kgIM40-
5、160mg/kgIP50mg/kgIVFentanyl-droperidol0.2-0.4ml/kgIPPentobarbital30-40mg/kgIV30-50mg/kgIP混合注射麻醉劑Ketamine+Xylazine87mg+13mg/kgIM,IPKetamine+Pentobarbital44mg+25mg/kg(K)IM,(P)IPKetamine+Acepromazine20-40mg+0.75mg/kgIM吸入麻醉劑HalothaneInduction:1-3%Maintenance:0.5-1.5%I
6、soflurane1-5%toeffectInhalationMethoxyfluraneInduction:2-4%Maintenance:0.5-1.5%EnfluraneInduction:3-4%Maintenance:1-3%止痛劑Meperidine3-5mg/kgIM,SC,IVButorphanol1-5mg/kgSCPentacozine2mg/kgSC不推薦使用的藥物ChloroformChloralHydrate300-450mg/kgIPChlorpromazineTribromoethanol30
7、0mg/kgIPIM:肌肉注射IV:靜脈注射SC:皮下注射IP:腹腔注射Inhalation:吸入Reference:1.實(shí)驗(yàn)動(dòng)物管理與使用指南。(中華實(shí)驗(yàn)動(dòng)物學(xué)會(huì)出版2005)2.Clinicallaboratoryanimalmedicine。(K.Hrapkiewicz,IowaStateUniversityPress1998)表3.倉(cāng)鼠(Hamster)麻醉劑量表藥物劑量途徑麻醉前給藥Atropin0.05-0.1mg/kgSC注射麻醉劑Ketamine200mg/kgIPPentobarbital70-90mg/
8、kgIPUrethane1500mg/kgIP混合注射麻醉劑Ketamine+Xylazine80-100mg+7-10mg/kgIPKetamine+Diazepam40-100mg+5mg/kgIPKetamine+Acetylpromazine150mg+5mg/kgIM吸入麻醉劑Halothan