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《運(yùn)動相關(guān)腦磁波之腦部信號源動態(tài)造運(yùn)動相關(guān)腦磁波之腦部信號源動態(tài)造》由會員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在行業(yè)資料-天天文庫。
1、運(yùn)動相關(guān)腦磁波之腦部信號源動態(tài)造運(yùn)動相關(guān)腦磁波之腦部信號源動態(tài)造影影ImagingCorticalSourceImagingCorticalSourceDynamicsofMovementDynamicsofMovement--RelatedRelatedNeuromagneticFieldNeuromagneticField計畫編號:NSC92-2218-E-010-005執(zhí)行期限:92年8月1日至93年7月31日主持人:陳麗芬助理研究員國立陽明大學(xué)神經(jīng)科學(xué)研究中心特約助理研究員臺北榮民總醫(yī)院教學(xué)研究部共同主持人:陳永昇助理教授國立交通大學(xué)資訊工
2、程學(xué)系謝仁俊主治醫(yī)師臺北榮民總醫(yī)院教學(xué)研究部教授暨所長國立陽明大學(xué)衛(wèi)生資訊與決策研究所計畫參與人員:劉宏毅、李宗展、黃勁霖、鄭志瑜研究生國立交通大學(xué)資訊工程學(xué)系MEG(MEG(MagnetoEncephaloGraphyMagnetoEncephaloGraphy))Vectorview:306channelsmanufacturedbyElektaInc.installedinTaipeiVeteransGeneralHospitalMEGSourceModelingMEGSourceModelingòForwardproblem:òInput:
3、thepositions,theamplitudeandtheorientationsofthesourcecurrentdipolesòOutput:toestimatethemeasureddatafromMEGsensorsòInverseproblem:òInput:asetofmeasureddataòOutput:toestimatetheparametersrepresentingthesourcecurrentdipoles,includingpositions,theamplitudeandtheorientationsForwa
4、rdModelForwardModel±Sourcemodel±Equivalentcurrentdipole(ECD)±Parameters:location,amplitude,andorientation±Fix,rotating,movingdipoles±Headmodel±relatedtothecomputationofvolumecurrent±Sphericalmodel±Boundaryelementmodel(BEM)±Finiteelementmodel(FEM)SourceModelSourceModelMaxwellMa
5、xwell‘‘sequationssequations::E??=ρε0E?×=??B?tB??=0BJ?×=()+?Eμ0ε0?tE:electricfieldε0:dielectricconstantB:magneticfieldμ:permeability0J:currentdensityρ:chargedensitySourceModel(cont.)SourceModel(cont.)òHeadisaconductorconsistingofHeadisaconductorconsistingofdifferentdifferenttis
6、suestissues..òUsingGreenUsingGreen’’stheorywithboundarystheorywithboundaryconditionwecanobtainthemagneticfieldconditionwecanobtainthemagneticfieldm()()μ0()?+?()()3?Br=B∞r(nóng)?∑σi?σi?∫Vrnir'×dd?dr'4πi=1?Si?()μ0∫p()3Br=r'×dddr'∞J4πGn(r):outwarddirectedunitnormalvectori+:conductivity
7、outsidethesurface-:conductivityinsidethesurfaced:r-rqHeadModelHeadModelòBoundaryBoundary--elementelement--methodmodel(BEM)methodmodel(BEM)òSphericalheadmodelSphericalheadmodelrr:sensorposition:sensorpositionrrq:positionofdipole:positionofdipoleqq:momentofdipole:momentofdipoleH
8、eadModel(cont.)HeadModel(cont.)òBecausetheBecausetheradialmag