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1、LecturesonWritingMedicalPaperAbstractsinEnglish第五講SCI收錄我國三種醫(yī)學(xué)雜志英文摘要賞析SCI是美國《科學(xué)引文索引》(ScienceCitationIndex)的縮寫。由于SCI數(shù)據(jù)庫具有學(xué)科全面、學(xué)術(shù)影響大、覆蓋國家廣泛等特點(diǎn),因而被其收錄檢索的期刊和論文分別被稱作國際主流期刊和國際主流科學(xué)。刊物或論文被SCI收錄和引用在一定程度上反映了該刊物或論文具有較高的學(xué)術(shù)水平和較大的國際影響力。我國目前被SCI收錄的科技期刊共60種,而臨床醫(yī)學(xué)類只有中華醫(yī)學(xué)雜志(英文版)、中國藥理學(xué)報和世界胃腸病雜志3種。一、中國藥理學(xué)報(
2、ActaPharmacologicaSinica)Sample1ActaPharmacologicaSinica2007February;28(2):238-245EffectofgenisteinonmouseblastocystdevelopmentinvitroAbstractAim:1)Toexaminethecytotoxiceffectsofgenistein,anisoflavonecompound,onearlypostimplantationembryonicdevelopmentinvitro.Methods:2)Mouseblastocystsw
3、ereincubatedinmediumwithorwithoutgenistein(25or50μmol/L)ordaidzein(50μmol/L)for24h.3)Cellproliferationandgrowthwasinvestigatedbydualdifferentialstaining,4)apoptosiswasanalyzedbyterminaldeoxynucleotidyltransferase-mediateddUTPnick-endlabeling(TUNEL)assay,and5)apoptoticornecroticcellswere
4、visualizedbyAnnexin-Vandpropidiumiodide(PI)staining.6)ImplantationandpostimplantationdevelopmentofembryosweremeasuredbyinvitrodevelopmentanalysisResults:7)TUNELstainingandAnnexin-V/PIstainingshowedthatgenisteindose-dependentlyincreasedapoptosisinmouseblastocysts,whiledaidzein,anothersoy
5、isoflavone,hadnosucheffect.8)Thepretreatmentoftheblastocystswithgenisteincausedfewercellsthanthecontrolgroupandthiseffectwasprimaryintheinnercellmass.9)Thegenistein-pretreatedblastocystsshowednormallevelsofimplantationonculturedishesinvitro,butsignificantlyfewergenistein-pretreatedembry
6、osreachedthelaterstagesofembryonicdevelopmentversusthecontrols,withmanyoftheformerembryosdyingatrelativelyearlystagesofdevelopment.Inaddition,10)genisteintreatmentdecreasedthedevelopmentofmorulasintoblastocysts,anddietarygenisteinwasfoundtoinducecellapoptosisanddecreasecellproliferation
7、inananimalassaymodelofembryogenesis.為主-動-賓-補(bǔ)(SVOC)結(jié)構(gòu)的被動語態(tài)Conclusions:11)Ourresultscollectivelyindicatethatgenisteintreatmentofmouseblastocystsinducesapoptosis,decreasescellnumbers,retardsearlypostimplantationblastocystdevelopment,andincreasesearly-stageblastocystdeathinvitro,wh