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1、聯(lián)合化療治療乳腺癌臨床治療體會(huì)【摘要】目的對(duì)于聯(lián)合化療治療乳腺癌的臨床治療體會(huì)進(jìn)行探討。方法本組75例,均為女性,年齡28~67歲,平均45?3歲,術(shù)后均經(jīng)病理證實(shí)。采用CAF方案29例,CMF方案25例,CEF方案12例,ET方案9例。所有患者化療4?6個(gè)療程,每個(gè)療程間隔28do結(jié)果本組病例就診后24h內(nèi)即明確診斷者70例(93?33%),就診后2~4d內(nèi)明確診斷5例(6?67%)。本組75例中出現(xiàn)化療藥物外溢至皮下發(fā)生疼痛、紅腫者5例,發(fā)生率6?7%靜脈炎19例,發(fā)生率25?3%胃腸道反應(yīng)71例
2、,發(fā)生率94?7%,骨髓抑制23例,發(fā)生率30?7%口腔炎26例,發(fā)生率34?7%脫發(fā)57例,發(fā)生率76%。75例聯(lián)合化療治療乳腺癌方案中,明顯好轉(zhuǎn)18例(24%),輕度好轉(zhuǎn)16例(21?33%),緩解不明顯7例(9令33%),無(wú)效34例(45?33%),有效率54?67%。結(jié)論化療藥物雖可最大限度的殺死癌細(xì)胞,但其不良反應(yīng)也不容忽視,化療期間運(yùn)用科學(xué)有效的護(hù)理方法,可以減輕化療中出現(xiàn)的各種不良反應(yīng)?!娟P(guān)鍵詞】聯(lián)合化療乳腺癌臨床治療體會(huì)Combinationchemotherapytreatmentf
3、orbreastcancerZHOULin.WangchengCountyPeople^sHospital,SingaporeBranchofHopeTown,Wangcheng410205,China【Abstract】ObjectiveCombinationchemotherapyfortreatmentofbreastcancertreatmenttoexplore?Methodslnthisgroupof75patientswerefemale,aged28to67years,mean45?3
4、years,wereconfirmedbypathologyafteroperation.29patientswithCAFprogram,CMFprogramin25cases,CEFprogramin12cases,ETprogramsin9cases?Allpatients4to6coursesofchemotherapy,eachtreatmentintervalof28d.ResultsAftertreatmentthegroupofcasesisdiagnosedwithin24h,70p
5、atients(93?33%),2~4daftertreatmentin5caseswerediagnosed(6?67%).75patientsinthisgroupappearedtosubcutaneouschemotherapyspilloccurs,painandrednessin5cases,theoccurrenceratewas6?7%;phiebitisin19cases,incidence25?3%;71casesofgastrointestinalreactions,theinc
6、idencewas94?7%,23casesofbonemarrowsuppression,theoccurreneerateof30?7%;stomatitisin26cases,incidence34?7%;hairlossin57cases,theoccurreneerateof76%?75casesofchemotherapytreatmentforbreastcancerprograms,significantimprovementin18cases(24%),mildimprovement
7、in16patients(21^33%),reliefobviousin7cases(9?33%),ineffectivein34patients(45?33%),effective54?67%.ConclusionAlthoughchemotherapydrugskillcancercellscanbemaximum,butitssideeffectscannotbeignored,chemotherapy,effectivecareduringtheapplicationofscientificm
8、ethods,chemotherapycanreducethevariousadversereactionsoccur.【Keywords]Combinationchemotherapy;Breastcancer;Clinicaltreatment;Experience乳腺癌是女性最常見(jiàn)的惡性乳腺癌之一,據(jù)資料統(tǒng)計(jì),發(fā)病率占全身各種惡性乳腺癌的7%?10%,在婦女僅次于子宮癌。它的發(fā)病常與遺傳有關(guān),以及40?60歲之間,絕經(jīng)期前后的婦女發(fā)病率較高。僅約1