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《心肌血流儲(chǔ)備分?jǐn)?shù)指導(dǎo)下短支架在冠脈長病變中的臨床應(yīng)用研究》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在工程資料-天天文庫。
1、心肌血流儲(chǔ)備分?jǐn)?shù)指導(dǎo)下短支架在冠脈長病變中的臨床應(yīng)用研究【摘要】目的：觀察心肌血流儲(chǔ)備分?jǐn)?shù)（FFR）指導(dǎo)下短支架在冠脈長病變中的臨床應(yīng)用。方法：選取本院在2014年1月-2015年1月期間收治的60例冠脈長病變患者作為研究對(duì)象，根據(jù)隨機(jī)數(shù)表法將所有患者分為對(duì)照組和觀察組，每組30例。對(duì)照組患者給予以長藥物支架（DES）植入，觀察組患者在FFR測(cè)定指導(dǎo)下，選擇最嚴(yán)重部位后予以DES植入，術(shù)后嚴(yán)格規(guī)范藥物治療，分別隨訪30d、3個(gè)月、6個(gè)月及1年，觀察記錄患者住院時(shí)間、支架使用數(shù)量及隨訪屮主要心臟不良事件。結(jié)果：對(duì)照組和觀察組患者植
2、入支架成功率均為100%（30/30）,比較差異無統(tǒng)計(jì)學(xué)意義（P>0.05）。觀察組患者植入支架數(shù)量和住院時(shí)間均顯著低于對(duì)照組，比較差異有統(tǒng)計(jì)學(xué)意義（P〈0?05）。術(shù)后隨訪1年，觀察組患者支架心絞痛、再狹窄率和再次再建術(shù)的發(fā)生率顯著低于對(duì)照組，比較差異均冇統(tǒng)計(jì)學(xué)意義（卩〈0?05）。結(jié)論：FFR指導(dǎo)下短支架應(yīng)用于指冠脈長病變，可顯著降低患者住院時(shí)間和支架使用數(shù)量，且顯著降低心絞痛、支架再狹窄及再次血運(yùn)建術(shù)等不良事件的發(fā)生率?！娟P(guān)鍵詞】冠狀動(dòng)脈；長病變；心肌血流儲(chǔ)備分?jǐn)?shù)；短支架；臨床應(yīng)用[Abstract】Objective：T
3、oevaluatetheclinicalapplicationofshortstentsincoronaryarterylesionsbymyocardialfractionalflowreserve(FFR)guided.Method：FromJanuary2014toJanuary2015,60patientswithcoronaryarterylonglesionswereselectedinourhospital,theywererandomlydividedintocontrolgroupandobservationg
4、roup,30casesineachgroup.Thecontrolgroupwastreatedwithlongdrug-elutingstentsimplantation,observationgroupwastreatedwithshortstentsundertheguidanceofmyocardialfractionalflowreserve.Strictlyregulatedrugtherapyaftersurgery,hospitalizationdays,numberofstentsandadverseeven
5、tsoftwogroupswerecomparedandfollowed30day,3months,6monthsand1yearafteroperation.Result：Thesuccessratesoftwogroupswereboth100%,thedifferencewasnostatisticallysignificant(P<0.05).Theimplantedstentnumberandlengthofhospitalstayinobservationgroupweresignificantlylowerthan
6、controlgroup,thedifferenceswerestatisticallysignificant(P<0.05).Postoperativefollow-upof1year,theincideneerateofanginapectoris,restenosisandbuildagainofobservationgroupweresignificantlylowerthancontrolgroup,thedifferenceswerestatisticallysignificant(P<0.05)?Conelusio
7、n：Scoreofmyocardialfractionalf1owreserveundertheguidaneeofshortbracketusedinlongcoronarylesions,cansignificantlyreducethein-hospitaltime,numberofstent,theanginapectoris,stentrestenosisandbloodsupplyagainbuildingtheincidenceofadverseevents.[Keywords]Coronaryartery；Lon
8、glesions；Myocardialfractionalflowreserve；Shortstent；Clinicalapplication冠狀動(dòng)脈（冠脈）介入治療（PCI）己經(jīng)成為治療冠心病的重要方法,冠脈病變長度＞20mm稱為冠脈長病變，約占冠脈介入治療的
