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1、啟肝毓坤湯治療卵巢早衰的效果[摘要]目的探討啟肝毓坤湯治療卵巢早衰患者的臨床效果。方法選擇2011年3月?2013年12月商丘醫(yī)學(xué)高等專科學(xué)校附屬醫(yī)院卵巢早衰患者85例,按就診順序分為兩組,單號(hào)為對(duì)照組(39例),雙號(hào)為治療組(46例)。對(duì)照組采用西笏雌孕激索序貫療法,治療組采用啟肝毓坤湯,兩組均連續(xù)治療3個(gè)月。比較兩組治療前后臨床癥狀和雌二醇(E2)、促卵泡激素(FSH)、黃體牛成激素(LH)的差異。結(jié)果治療組總冇效率為89.13%,對(duì)照組為79.49%,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P〈0.05)。治療后,治療組心煩急躁、腰酸墜脹消失率(89.47%.
2、87.50%)均高于對(duì)照組(77.27%、73.68%),差異均有統(tǒng)計(jì)學(xué)意義(P<0.05)。治療前后治療組E2:(15.39土6.23)、(90.47±7.02)ng/L]、FSH[(81.65土18.12)、(31.25±4.12)U/L]、LH[(42.18±5.52)、(23.46±4.09)U/L]水平比較,差異均有統(tǒng)計(jì)學(xué)意義(P<0.05);治療前后對(duì)照組E2[(14.28±5.89)、(57.62±4.75)ng/L]>FSH[(79.24土16.72)、(35.47±5.19)U/L]、LH[(4.13±4?69)、(22.25±4.1
3、3)U/L]水平比較,差異均有統(tǒng)計(jì)學(xué)意義(P<0.05)o治療后兩組E2水平比較,差異有統(tǒng)計(jì)學(xué)意義(P<0.05)o結(jié)論啟肝毓坤湯可冇效改善由卵巢早衰引起的激素水平變化,且能緩解其臨床癥狀,臨床療效較好。[關(guān)鍵詞]啟肝毓坤湯;卵巢早衰;促性腺激素[中圖分類號(hào)]R711.75[文獻(xiàn)標(biāo)識(shí)碼]A[文章編號(hào)]1673-7210(2016)03(a)-0108-04EffectofQiganyukunDecoctioninthetreatmentofpatientswithprematureovarianfailureWANGXueliWANGHuahangJI
4、ANGBoHUJunmingYANJunyingDepartmentofTraditionalChineseMedicine,theAffiliatedHospitalofShangqiuMedicalCollege,lie,nanProvince,Shangqiu476005,China[Abstract]ObjectiveToinvestigatetheclinicaleffectofQiganyukunDecoctioninthetreatmentofpatientswithprematureovarianfailure?Methods85pat
5、ientswithprematureovarianfailureintheAffiliatedHospitalofShangqiuMedicalCollegefromMarch2011toDecember2013wereselected,whoweredividedintotwogroupsaccordingtovisitingsequence,46casesintreatmentgroupand39casesinthecontrolgroup.Patientsinthecontrolgroupweretreatedbywesternmedicines
6、equentialtherapyofestrogenandprogesterone,thetreatmentgroupwastreatedwithQiganyukimDecoction,twogroupswerecontinuoustreatedfor3months.Thedifferencesofclinicalsymptomsandthelevelsofhormonesbeforeandaftertreatmentwerecompared.ResultsThetotaieffectiverateofthetreatmentgroupwas89.13
7、%,thecontrolgroupwas79.49%,thedifferencewasstatisticallysignificant(P[Keywords]QiganyukunDecoction;Prematureovarianfailure;Gonadotropingonadalhormone卵巢早衰(prematureovarianfailure,POF)是指女性在40歲以前因某種原因引起的以閉經(jīng)、不孕、雌激素水平下降以及促卵泡激素(FSH)水平升高(FSH>40U)為特征的一種疾?。?]。發(fā)病率占婦女總?cè)藬?shù)的1%~3%[2]。山于丁作、生活壓力
8、不斷增大等因素的影響,該病發(fā)病率逐年上升,口患者發(fā)病年齡逐年下降,對(duì)該人群的身心健康造成嚴(yán)重威