資源描述：
《冠狀病毒Coronavirusl論文-2017 The role of epidermal growth factor receptor (EGFR) signaling in SARS coronavirus-induced pulmonary fibrosis.pdf》由會員上傳分享，免費在線閱讀，更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫。
1、AcceptedManuscriptTheroleofepidermalgrowthfactorreceptor(EGFR)signalinginSARScoronavirus-inducedpulmonaryfibrosisThiagarajanVenkataraman,MatthewB.FriemanPII:S0166-3542(16)30797-5DOI:10.1016/j.antiviral.2017.03.022Reference:AVR4042Toappearin:AntiviralResearchReceivedDate:20
2、December2016AcceptedDate:28March2017Pleasecitethisarticleas:Venkataraman,T.,Frieman,M.B.,Theroleofepidermalgrowthfactorreceptor(EGFR)signalinginSARScoronavirus-inducedpulmonaryfibrosis,AntiviralResearch(2017),doi:10.1016/j.antiviral.2017.03.022.ThisisaPDFfileofanuneditedma
3、nuscriptthathasbeenacceptedforpublication.Asaservicetoourcustomersweareprovidingthisearlyversionofthemanuscript.Themanuscriptwillundergocopyediting,typesetting,andreviewoftheresultingproofbeforeitispublishedinitsfinalform.Pleasenotethatduringtheproductionprocesserrorsmaybe
4、discoveredwhichcouldaffectthecontent,andalllegaldisclaimersthatapplytothejournalpertain.ACCEPTEDMANUSCRIPTTheRoleofEpidermalGrowthFactorReceptor(EGFR)SignalinginSARSCoronavirus-InducedPulmonaryFibrosisThiagarajanVenkataramanandMatthewBFrieman*DepartmentofMicrobiologyandImm
5、unologyUniversityofMarylandatBaltimore685WestBaltimoreSt.Room380Baltimore,MD21201MANUSCRIPT*CorrespondingauthorMatthewFriemanUniversityofMarylandatBaltimoreDepartmentofMicrobiologyandImmunology685WestBaltimoreSt.Room380Baltimore,MD21201mfrieman@som.umaryland.edu/410-706-25
6、39ACCEPTEDKeywords:Woundhealing,SARS-CoV,EGFR,fibrosisACCEPTEDMANUSCRIPTAbstractManysurvivorsofthe2003outbreakofsevereacuterespiratorysyndrome(SARS)developedresidualpulmonaryfibrosiswithincreasedseverityseeninolderpatients.AutopsiesofpatientsthatdiedfromSARSalsoshowedfibro
7、sistovaryingextents.PulmonaryfibrosiscanbeoccasionallyseenasaconsequencetoseveralrespiratoryviralinfectionsbutismuchmorecommonafteraSARScoronavirus(SARS-CoV)infection.Giventhethreatoffutureoutbreaksofseverecoronavirusdisease,includingMiddleEastrespiratorysyndrome(MERS),iti
8、simportanttounderstandthemechanismsresponsibleforpulmonaryfibrosis,soastosupportthedevelo
