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1、萬方數(shù)據(jù)基礎(chǔ)醫(yī)學中國組織工程研究與臨床康復舅11卷第巧期2007—09—02出版JournalofClinicalRehabilitativeTissueEngineeringResearchSeptember2,2007V01．11，No35聚羥基丁酸己酸酯／聚碳酸亞丙酯共混材料作為血管組織工程支架的性能特征☆張玲1，敖強2，賀慶1，王干1，奚靜1，公衍道1，張秀芳11StateKeyLaboratoryofBiomembrane-MembraneBioengineering，DepartmentofBio[ogicalSciencesandBiotec
2、hnology，TsinghuaUniversity，Beijing100084，China；2InstituteofCerebraINeweDisease，ResearchAcademyofLifeSciences，TsinghuaUniversity，Beijing100049．ChinaZhangLing☆Studyingdoctorate．LaboratoryforStareKeyBiomembrane．MembraneBIoenglneerIng，DepartmentofBiologicalSciencesandBiotechnology，Tsi
3、nghuaUniversity．Beijing100084，Chinazlin903@mailstsinghuaeducnCOrresDOndencetO：ZhangXiu-fang，Professor，StateKeyLaboratoryofBiomembrane-MembraneBIOengIneerfng，DepartmentofBiologicalSciencesandBiotechnoiogy，TsinghuaUniversity，Beijing100084。ChinaPropertiesofpoly(3-hydroxybutyrate·co·3
4、-hydroxyhexanoate)／polypropylenecarbonateblendedmaterialsasascaffoldforbloodvesseltissueengineeringAbstractAIM：ToimprovethemechanicaIpropertyofpoly(3-hydroxybutyrate—co-3一hydroxyhexanoate)(PHBHHx)andprocessingabilityofpolypropylenecarbonate(PPC)，thePHBHHxandPPCwereblendedinsolvent
5、andmadeintofilmsandtubularscaffolds．Theadhesionofrabbilaortasmoothmusclecell(RaSMC)onthef¨msandthemechanicaIpropertyofIubularscaffoldswereevaluatedtoselectapropermaterialasscaffoldforbloodvesseItissueengineeringMETHoDS：TheexperimentwasconductedjntheStateKeyLaboratoryofBiomembranea
6、ndMembraneBioengineering，DepartmentofBiologicaISciencesandBiOtechn0IOgy，TsinghuaUniversityfrOmAugust2006toApril2007．(DRaSMCswereincubatedonthef¨msfromdifferenlweightratiosofPHBHHx／PPCblendedsolution(PHBHHx：PPC=0：10，3：7，5：5，7：3，and10：0)for24hoursandtheamountsofadhesionondifferentf¨
7、msweredetectedbvCCK-8kit．②Tubularscaffoldswerepreparedusingthermally—inducedphaseseparation(TIPS)andfreeze．dryingmethods．a(chǎn)ndthentheyweredippedintotheirsolutionsrespectivelyanddriedinairAdriedmembranewasformedonthesurfaceofscaffolds．Themorphologyofthescaffoldswasobservedbyscanninge
8、lectronmicroscopy(SEM)：theporosit
