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《肌酸激酶同工酶、肌鈣蛋白及超敏C-反應(yīng)蛋白聯(lián)合檢測對手足口病患兒心肌損害臨床意義.doc》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在工程資料-天天文庫。
1、肌酸激酶同工酶、肌鈣蛋白及超敏c-反應(yīng)蛋白聯(lián)合檢測對手足口病患兒心肌損害臨床意義［摘要］目的探索肌酸激酶同工酶、肌鈣蛋白及超敏c-反應(yīng)蛋白聯(lián)合檢測對手足口病患兒心肌損害的臨床意義。方法選取本院2011年6月?2011年12月期間診治的105例手足口病患兒，全部納入觀察組；另隨機(jī)選取同期門診健康體檢兒童60例，納入對照組；觀察組和對照組均開展肌酸激酶(CK)、肌酸激酶同工酶(CK-MB).肌鈣蛋白(cTnl)及超敏C-反應(yīng)蛋白(hs-CRP)等指標(biāo)的水平檢測。結(jié)果觀察組患兒心肌損害率為47.62%,對照組為6.67
2、%,兩組比較觀察組顯著高于對照組(P<0.01)；觀察組患兒的CK、CK-MB、cTnl及hs-CRP檢測水平均明顯髙于健康對照組兒童(P均〈0.01)o結(jié)論在對手足口病患兒開展早期診治時(shí)，應(yīng)緊密結(jié)合心肌酶、肌鈣蛋白、C-反應(yīng)蛋白等臨床檢測指標(biāo)結(jié)果，早期診斷手足口病小兒是否發(fā)生心肌損壞，以及早采取治療措施。［關(guān)鍵詞］手足口?。恍募p害；肌酸激酶；CK-MB、cTnl及hs-CRP水平檢測［中圖分類號］R725.1［文獻(xiàn)標(biāo)識(shí)碼］B［文章編號］1674-4721(2012)07(b)-0107-02Clinicals
3、ignificanceofjointdetectionofcreatinekinaseisoenzymes,troponinandhigh-sensitivityC-reactiveproteinonmyocardialdamageinchildrenwithhandfootandmouthdiseaseWEIHuaThePeople"sHospitalofPeiCountyinJiangsuProvince,PeiCounty221600,China[Abstract]ObjectiveToobservethe
4、clinicalsignificanceofjointdetectionofcreatinekinaseisoenzymes,troponinandhigh-sensitivityC~reactiveproteinonmyocardialdamageinchildrenwithhandfootandmouthdisease?MethodsOnehundredandfivechildrenwithhandfootandmouthdiseasetreatedinourhospitalfromJune2011toDec
5、ember2011wereselectedandallincorporatedintotheobservationgroup.And60childrenwithoutpatienthealthphysicalexaminationofthecorrespondingperiodwerechosenrandomlyandincorporatedintothecontrolgroup.Theobservationgroupandthecontrolgroupalldetectedtheindexlevelofcrea
6、tinekinaseisoenzymes,troponinandC-reactiveprotein,etc?ResultsThemyocardialdamagerateoftheobservationgroupwas47.62%,asforthecontrolgroup,themyocardialdamageratewas6.67%.Bycomparison,theobservationgroupwassignificantlyhigherthanthoseinthecontrolgroup(P<0.01).Th
7、edetectionlevelofcreatinekinaseisoenzymes,troponinandC~reactiveproteininchildrenoftheobservationgroupwerehigherobviouslythanthecontrolgroupofhealthychildren(P<0.01)?ConclusionInearlydiagnosisandtreatmentofchildrenwithhandfootandmouthdisease,thedetectionofclin
8、icalindexesofcreatinekinaseisoenzymes,troponinandC-reactiveproteinshouldbecombined,anddiagnosewhetherthepatientswithhandfootandmouthdiseaseoccurmyocardialdamagetotakeearlytreatmentmeasure
