資源描述:
《PET/CT對TACE聯(lián)合RFA治療原發(fā)性肝癌的療效評價-論文.pdf》由會員上傳分享,免費在線閱讀,更多相關(guān)內(nèi)容在應(yīng)用文檔-天天文庫。
1、·34·醫(yī)刊2013年11月第40卷第22期ChineseJournalofPracticalMedicineNov.2013.Vol_40.No.22PET/CT對TACE聯(lián)合RFA治療原發(fā)性肝癌的療效評價蔡越飛鐘勝冼重楊譚小明賈志斌高中山【摘要】目的探討PET/CT在經(jīng)動脈導(dǎo)管栓塞化療(TACE)聯(lián)合射頻消融(RFA)治療原發(fā)性肝癌后的應(yīng)用價值。方法本組21例原發(fā)性肝癌患者共有31個病變,腫瘤最大徑為1.0—12.5cm。其中15例為初治病例,6例為肝癌手術(shù)后復(fù)發(fā)。經(jīng)過TACE聯(lián)合RFA治療后3周,對比CT和PET/CT檢查的結(jié)果。如發(fā)現(xiàn)有腫瘤殘留,在1周內(nèi)
2、對其再次行RFA治療。結(jié)果21例患者經(jīng)一次TACE聯(lián)合一次RFA治療3周,經(jīng)病變區(qū)域活檢及數(shù)字減影血管造影等檢查發(fā)現(xiàn)19例有部分腫瘤殘留,腫瘤殘留最大徑為0.5~3.5cm。cT增強掃描檢查檢出10例,檢出率為52.6%;PET/CT檢出有17例殘留,檢出率為89.5%。根據(jù)PET/CT檢查結(jié)果,在1周內(nèi)再次行RFA治療,PET/CT檢查發(fā)現(xiàn)16例患者腫瘤無殘留,1例患者3周后復(fù)查PET/CT發(fā)現(xiàn)肝內(nèi)病變未完全控制,行第3次RFA。結(jié)論原發(fā)性肝癌經(jīng)TACE聯(lián)合RFA治療后,PET/CT對判斷腫瘤殘留以及指導(dǎo)進一步RFA治療較CT檢查具有更大的優(yōu)勢。【關(guān)鍵詞】原發(fā)
3、性肝癌;射頻消融;經(jīng)動脈導(dǎo)管栓塞化療;PET/CTEficacyevaluationoftranscatheterarterialchemo-embolizationcombinedwithradiofrequencyablationonpatientswithhepatocellularcarcinomabyPET/CTCAIYue,ZHONGSheng,XIANChong—yang,TANXiao—ming,JlAzhi—bin,GAOZhong—shan.DepartmentofInterventionalRadiol—ogy,DonghuaHospita
4、lofDongguan,Dongguan523110,China【Abstract】ObjectiveToinvestigatethevalueofPEI1/cTinjudgingtumorresidueofhepato—cellularcarcinoma(HCC)aftertreatedbytranscatheterarterialchemo—embolization(TACE)combinedwithradiofrequencyablation(RFA).MethodsTwentyoneHCCpatientswith31lesions,1.0—12.5cmi
5、ndiameter.weretreatedinourhospitalfromDecember2009toDeeember2011.0fthe21patients.15caseswerenaivepatientswith21lesions,6patientswererelapsedafterhepatectomy.TheresultsofCTandPET/CTofthe21patients3weeksaftertreatmentofTACEcombinedwithRFAwerecompared.Iftumorresiduewasdictated,afurtherR
6、FAtreatmentwouldbeappliedwithinoneweek.ResultsOfthe21HCCpatientsthatreceivedonecourseofTACEcombinedwithRFA,19caseshadtumorresidueswhichwereconformedbyfineneedlebiopsyanddigitalsubstractionangiography(DSA).CTonlydetec—ted10positivecases;however,PET/CTdetected17positivecases.Positivera
7、teofCTwas52.6%,andthatofPET/CTwas89.5%.AccordingtotheresultsofPET/CTofthe17patients.a(chǎn)fterthesecondcourseofRFA.16patientshadriotumorresidue。lcasesurvivedwithuncontrolledlesions3weeksaftertreatment.ConclusionsPET/CTisbetterthanCTiniudgingtumorresidueofHCCaftertreatmentofTACEcombinedwit
8、hRFA.a(chǎn)ndingu