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《抑肝扶脾清熱利濕法對廣東地區(qū)腹瀉型腸易激綜合征患者血漿胃腸激素含量的影響-論文.pdf》由會員上傳分享,免費在線閱讀,更多相關(guān)內(nèi)容在行業(yè)資料-天天文庫。
1、第21卷第1O期第509頁中國中西醫(yī)結(jié)合消化雜志VO121N010P5092013年1O月ChinJIntegrTradWestMedDigoct2013doi:10.3969/j.issn.1671—038X.2013.10.002抑肝扶脾清熱利濕法對廣東地區(qū)腹瀉型腸易激綜合征患者血漿胃腸激素含量的影響常東,李健,馮春霞。,唐純志。,劉予志。,樊亞巍,李輝,何方(武警廣東邊防總隊醫(yī)院消化內(nèi)科,廣東深圳518029;深圳市中醫(yī)院消化內(nèi)科,廣東深圳518033;。廣州中醫(yī)藥大學科研處,廣東廣州510407)摘要:[目的]觀察抑肝扶脾清熱利濕法對廣東地區(qū)腹瀉型腸易激綜合征(dia
2、rrheatypeirritablebowelsyn—drome,mS-D)患者血漿胃動素(MTL)、血管活性腸肽(VIP)、生長抑素(SS)、膽囊收縮素(CCK)的影響,并探討其作用機制。[方法"]160例IK%D患者隨機分為2組,中藥組采用易激靈2號方,煎取200ml,早晚分服;西藥組口服馬來酸曲美布丁片(商品名:舒麗啟能)0.1g/次、枯草桿菌二聯(lián)活菌腸溶膠囊(商品名:美常安)0.5g/次,3次/d;2組療程均為4周。另選2O例健康體檢者為正常對照組。[結(jié)果]IBD患者血漿CCK、MTL水平較正常對照組明顯增高(P
3、TL水平明顯降低(P
4、swithdiarrheatypeirritablebowelsyndromeinGuangdongdistrictCHANGDong,LIJian,F(xiàn)ENGChun—xia。,TANGChun—zhi。LIUZi—zhi。FANYa—weiLIHuiHEFang(DepartmentofDigestiveDiseases,ShenzhenHospital,ChinesePeople’SArmedPoliceForces,Shenzhen518029,China;。DepartmentofDigestiveDiseases,ShenzhenHospitalofTraditio
5、nlChineseMedicine,Shenzhen518033,China;。ScientificResearchOffice,GuangzhouUniversityofChineseMedicine,Guangzhou510407,China)Correspondingauthor:CHANGDong,E—mail:wjchangdong@sina.cornAbstract:I-Objective]Toobservetheeffectofsoothingliverandinvigoratingspleen,clearingawayheatandeliminatingdam
6、pnessonMTL,VIP,SS,CCKinpatientswithdiarrheatypeirritablebowelsyndrome(IBD)inGuangdong.[Methods]Thetotalof160patientswithIBDwereassignedto2groups:ChinesemedicineGroupwastreatedwithYUILING-2,decocted200ml,twicedailybyoraladministration;WesternmedicineGroupwastreatedwithTrimebutineMaleateTable
7、ts0.1gandMeichangan0.5g,3timesdailybyoraladministration.Thetherapeuticcoursewas4weeksfora11.JResultslTheplasmaCCK,MTLweresig—nificantlyhigherinIBS-Dpatientsthaninthenormalgroup(P~0.01).Aftertreatment。theplasmaCCK。MTLweresignificantlylowerinIBDpatientsofC