資源描述:
《代謝綜合征冠心病患者冠狀動脈病變程度及相關(guān)因素的探討》由會員上傳分享,免費在線閱讀,更多相關(guān)內(nèi)容在學術(shù)論文-天天文庫。
1、代謝綜合征冠心病患者冠狀動脈病變程度及相關(guān)因素的探討作者:錢風華,奚耀,錢義明,顧曉剛,吳士延,巫亞穎,頊志兵【摘要】目的探討代謝綜合征(MS)合并冠心病患者冠狀動脈粥樣硬化病變程度及相關(guān)因素之間的聯(lián)系,研究MS合并冠心病患者體重指數(shù)(BMI)與冠狀動脈病變程度的相關(guān)性。方法回顧性分析152例經(jīng)冠狀動脈造影確診為冠心病的患者,分為MS組(88例)和非MS組(64例),比較兩組患者的冠狀動脈Gensini評分及程度、左心室射血分數(shù)(LVEF)、血壓、體重指數(shù)(BMI)、空腹及餐后2h血糖、血脂及超敏C反應(yīng)蛋白(hs-CRP)的差異。同時根據(jù)MS患者的BMI分為重
2、度MS組(46例)和輕度MS組(42例),比較兩組患者的冠狀動脈Gensini評分及病變程度、LVEF、血壓、BMI、空腹及餐后2h血糖、血脂及hs-CRP的差異。結(jié)果MS組患者的冠狀動脈Gensini評分和病變程度、LVEF、血壓、BMI、空腹及餐后2h血糖、血脂和hs-CRP與非MS組相比,差異有顯著性(P<0.05或P<0.01);重度MS組患者的冠狀動脈Gensini評分及病變程度、BMI、總膽固醇、甘油三酯、高密度脂蛋白、hs-CRP與輕度MS組相比,差異有顯著性(P<0.05或P<0.01);相關(guān)回歸分析顯示MS患者冠狀動脈病變程度與BMI存在正相
3、關(guān)。結(jié)論MS合并冠心病可加重冠狀動脈的病變程度,兩者存在正相關(guān);應(yīng)當及早干預MS以減少冠心病的病變程度。11【關(guān)鍵詞】代謝綜合征;冠心?。还跔顒用}造影;相關(guān)因素[Abstract]ObjectiveTodiscusstheimpairmentofcoronaryarteryandrelatedfactorsinpatientswithcoronaryatheroscleroticheartdisease(CAD)andmetabolicsyndrome(MS).Andtoexploretherelationshipbetweenbodymassindex(BM
4、I)andthedegreeoftheimpairmentofcoronaryarteryinpatientswithCADandMS.Methods152CADpatientsdiagnosedbycoronaryarteriographyweredividedintotwogroups,MSgroupof88casesandnon-MSgroupof64cases.Gensiniscoringoftheimpairmentofcoronaryarterymeasuredbyechocardiography,bloodpressure,BMI,fasting
5、bloodglucose,2hoursbloodglucoseaftermeal,bloodlipidandhi-sensitiveC-reactiveprotein(hs-CRP)ofthetwogroupswerecomparedrespectively.The88MSpatientsweredividedintotwogroupsaccordingtotheseverityofMS,theseveregroupof46casesandtheslightgroupof42cases.Gensiniscoringoftheimpairmentofcorona
6、ryartery,LVEF,bloodpressure,BMI,fastingbloodglucose,2hoursbloodglucoseaftermeal,bloodlipid,fibrinogen,BNPandhs-CRPofthetwogroupswerecomparedaswell.ResultsThereweresignificantdifferencebetweenMSgroupandnon-MSgroupofGensiniscoringoftheimpairmentof11coronaryartery,bloodpressure,BMI,fas
7、tingbloodglucose,2hoursbloodglucoseaftermeal,bloodlipidandhs-CRP(P<0.05orP<0.01).TherewerealsosignificantdifferencebetweenthesevereMSgroupandtheslightMSgroupofGensiniscoringoftheimpairmentofcoronaryartery,BMI,totalcholesterol,triglyceride,HDLandhs-CRP(P<0.05orP<0.01).Therewaspositiv
8、ecorrelationbetween