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1、沙眼衣原體和解脲支原體感染與輸卵管性不孕癥關(guān)系的研究作者何秋紅指導(dǎo)者摘要目的探討女性生殖道沙眼衣原體(CT)和解脲支原體(UU)感染與輸卵管性不孕癥的關(guān)系。方法檢測(cè)200例不孕癥患者(原發(fā)不孕癥81例,繼發(fā)不孕癥119例)和140例有正常生育史的女性宮頸黏夜的CT(膠體金技術(shù))和UU(液體培養(yǎng)法),于檢查后1~6個(gè)月內(nèi)月經(jīng)后3—7d進(jìn)行子宮輸卵管造影或腹腔鏡檢查,了解輸卵管通暢情況。結(jié)果不孕婦女CT和UU陽性率分別為69例(34.5%)和100例(50.0%),其中,輸卵管堵塞患者中,UU陽性率為2
2、8.0%,CT陽性率為21.5%,合并感染者16.5%;而輸卵管通暢患者中,UU陽性率為12.0%,CT陽性率為7.0%,合并感染者4.5%。二者相差均顯著(P<0.05)。對(duì)照組CT和UU陽性為16例(11.4%)和26例(18.05%)合并感染者9例(6.4%)結(jié)論支原體及衣原體感染在輸卵管性不孕癥的發(fā)病中起重要作用,是不孕癥的主要原因。關(guān)鍵詞沙眼衣原體解脲支原體輸卵管不孕ChlamydiatrachomatisandUreaplasmaurealyticuminfectionandtubali
3、nfertilityrelations?Abstract:ObjectiveToinvestigatetherelationshipofthefemalegenitaltractChlamydiatrachomatis(CT)andUreaplasmaurealyticum(UU)infectionandtubalinfertility?TheDepartment.?Methoddetected200casesofinfertilitypatients(primaryinfertility,81ca
4、sesofsecondaryinfertility,119cases)and140casesofwomenwithnormalreproductivehistoryofcervicalstickynightCT(colloidalgold)andUU(liquidculture?),3-7dintheinspectionwithinasixmonthperiodafterhysterosalpingographyorlaparoscopy,understandingoftubalpatency.?R
5、esultsofinfertilewomenwithCTandUUpositiverateswere69cases(34.5%)and100cases(50.0%),whichblockedfallopiantubesinpatientswithUUpositiveratewas28.0%,locatedintheTomb,DongShenJiabang,deferthenextdayfocusedontheassassination.Linping,Zhejiang,1ofwhichliquorw
6、inemasters(WuzhensaidinformationisCarpenter),whogotAfewbayonets,duetomissedfatal,whennightcameCTpositiveratewas21.5%,co-infection16.5?%;tubalpatencyinpatientswithUU-positiverateof12.0%ofCT-positiveratewas7.0%,4.5%oftheconcurrentinfection.?Thedifference
7、wassignificantly(P<0.05).?ControlgroupofCTandUUpositivewas16cases(11.4%)and26cases(18.05%)co-infectionin9cases(6.4%)ConclusionMycoplasmaandChlamydiainfectionsintheincidenceoftubalinfertilityplaysanimportantroleis?Themainreasonforinfertility.?KeywordsCh
8、lamydiatrachomatisUreaplasmaurealyticumtubalinfertility沙眼衣原體(CT)和解脲支原體(UU)是最常見的性傳染病原體,不僅造成廣泛的生殖道感染,并且導(dǎo)致不育,其發(fā)病率近年呈上升趨勢(shì)[1]。其病理機(jī)制為上述兩者均能侵犯生殖系統(tǒng)黏膜層,使其發(fā)生慢性炎癥,長(zhǎng)期反復(fù)的慢性炎癥最終導(dǎo)致官腔的閉塞,尤其是輸卵管的閉塞會(huì)直接導(dǎo)致不育不孕。此外,UU和CT的感染還能導(dǎo)致內(nèi)環(huán)境的改變,特別是受孕環(huán)境的改變,由于UU可以吸附于精子頭部