資源描述：
《used in migraine用于偏頭痛的藥物課件》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在教育資源-天天文庫(kù)。
1、DRUGSUSEDINMIGRAINEMd.AmranHowladerMigraineisaneurologicalsyndromethatcancauseawiderangeofsymptomsduringanattack.Themostcommonlythoughtofsymptomisheadache.Itiswidespreadinthepopulation.IntheU.S.,18%ofwomenand6%ofmenreporthavinghadatleastonemigraineepisodeinthepreviousyear,withseriousnessrangingf
2、romanannoyancetoalife-threateningand/ordailyexperience.OverviewUsuallymigrainecausesepisodesofsevereormoderateheadache(whichisoftenone-sidedandpulsating)lastingfromfourto72hours,accompaniedbygastrointestinalupsets,suchasnauseaandvomiting,andaheightenedsensitivitytobrightlights(photophobia)andnoi
3、se(phonophobia).Approximatelyonethirdofpeoplewhoexperiencemigrainegetaprecedingaura,inwhichapatientsensesastrangelightorunpleasantsmell.ThewordmigraineisFrenchinoriginandcomesfromtheGreekhemicrania,asdoestheOldEnglishtermmegrim.Literally,hemicraniameans"half(the)head".Migraines'secondarycharacte
4、risticsareinconsistent.Triggersprecipitatingaparticularepisodeofmigrainevarywidely.Theefficacyofthesimplesttreatment,applyingwarmthorcoolnesstotheaffectedareaofthehead,variesbetweenpersons,sometimesworseningthemigraine.Aparticularmigrainerescuedrugmaysometimesworkandsometimesnotworkinthesamepati
5、ent.Somemigrainetypesdon'thavepainormaymanifestsymptomsinpartsofthebodyotherthanthehead.Availableevidencesuggeststhatmigrainepainisonesymptomofseveraltomanydisordersoftheserotonergiccontrolsystem,adualhormone-neurotransmitterwithnumeroustypesofreceptors.Twodisorders—classicmigrainewithaura(MA,ST
6、G)andcommonmigrainewithoutaura(MO,STG)—havebeenshowntohaveageneticfactor.Studiesontwinsshowthatgeneshavea60to65%influenceonthedevelopmentofmigraine.Additionalmigrainetypesaresuspectedandcouldbeproventobegenetic.Migraineunderstoodasseveralormanydisorderscouldexplaintheinconsistencies,especiallyif
7、asinglepatienthasmorethanonegenetictype.ClassificationMigraineshavebeenclassifiedbytheInternationalHeadacheSocietywhichperiodicallyrevisestheirclassification.DefiningseverityofpainInadditiontoclassifyingthetypeofheadache,the
