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1、萬方數(shù)據(jù)·216·生堡緒擅塑夔吸盤壺墊!Q璽!旦笠墅鲞筮i魍g匭!』堂墮啞墮!,鱉!!Q!Q,型:塑,№:墨participationintheup-regulat/enofmanno∞r(nóng)eceptoractivity.Jlmmunol。2005.175:2227-2236.[10]I(aIIgPB,AzadAK,TorrelhsJB,etaLnehumanmaeruphageInannosereceptordirectsMycobactedumtuberculosisiipoarabinomannan·mediat
2、edphagosomebiogenesi暑.JExpMed.2005.202:98%999.[11]劉平,郭述良。羅永艾.Dc.SIGN分子與結(jié)核病的發(fā)生.中華結(jié)核和呼吸雜志,2007,30:458-461.[12]MaedaN,NigouJ,Herrmann兒,otaL強(qiáng)ecelsurfacereceptorDE—SIGNdiserimihatesb咖eenMyeobaetetiumspeciesthroughselectiverecognitionoftheinsnno$ecapsonlipoarabinoman
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4、08,3:e1388.[15]BarreiwLB,Neyrolles0,BabbCL,etaLPromotervariationintheDC··SIGN··encodinggeneCD209isassociatedwithtuberculosis.PLoSMed,2006。3:e20.[16]Neyroles0,GicquelB,Quintana-MurciLTowardsacrucialroleforDC-SIGNintuberculosisandk-yon正TrendsMicrobiol,2006。14:383
5、-387.[17]G6mezLM,AnayaJM,Sierra.FilardiE,etaLAnalysisofDc.sIGN(CD209)functionalvariantsinpatientswithtuberculosis.Humlmmunol。2006。67:808-811.[18]Ben·AliM,BarreimLB,ChabbouA,etaLPromoterandneckregionlengthvariationofDC—SIGNiBnotassociatedwithsusceptibilitytotube
6、rculosisinTunisianpatients.HumImmunol。2007,68:908-912.[19]BarreiroLB,Neyroiles0,BabbCL,eta1.LengthvariationofDC.-SIGNandL-SIGNneck-regionhas40impactontuberculosissusceptibility.Humlmmunol,2007,68:106·112.[20]RothfuchsAG,BaficaA,F(xiàn)eIIgCG,eta1.Dectin-1interactionw
7、ithMycobacteriumtuberculosisleadstoenhancedIL.12p40productionbysplenicdendriticcells.JImmunai,2007,179:3463.3471.[21]JoEkMycobacterialinteractionwithinnatereceptors:7rLRs,C—typehotins,andNUhCurtOpinInfectDis,2008,21:279-286.從肺康復(fù)指南的更新看肺康復(fù)研究的進(jìn)展孟申1997年,美國胸科醫(yī)生學(xué)院(AC
8、CP)和美國心血管肺康復(fù)協(xié)會(ACCVP)發(fā)表了肺康復(fù)的循證醫(yī)學(xué)指南(簡稱舊指南)?,并于2007年對該指南迸行了更新(簡稱新指南)瞄]。我們從中可以看到,10年來的研究結(jié)果進(jìn)一步證明肺康復(fù)對于慢性呼吸系統(tǒng)疾病患者有效HJ。筆者在此對該指南修訂前后的變化進(jìn)行綜述。1.肺康復(fù)的定義及分級:新指南采用2006年ATS/ERS的定義【4J:“肺康復(fù)是