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1、超聲對周圍神經慢性卡壓損傷引起神經形態(tài)學變化的研究張?zhí)N楚陳定章王文玲高磊(武警北京總隊第三醫(yī)院超聲科100039}【摘要】目的：研宄超聲對周圍祌經慢性卡壓損傷所引起的祌經形態(tài)學變化。方法：取解放軍總醫(yī)院實驗動物中心提供的月齡為10-12個月的健康家兔20只，隨機分為5組，每組4只，分別為對照組、卡壓2周組、卡壓4周組、卡壓6周組以及卡壓8周組。參考Mackinnons等設計方案建立坐骨祌經慢性卡壓模型，卡壓2周組、4周組、6周組、8周組分別在在術后2周、4周、6周、8周時對家兔坐骨神經進行超聲觀察和電生理觀察，對照組取術后8周時間進行上述觀察。結果：隨著卡壓時間的延訟
2、，坐骨祌經增粗越明顯，與對照組相比差異有統(tǒng)計學意義(P<0.05)。內部回聲紊亂加重，而家兔MNCV、SNCV速度減慢，與對照組比較只有組間差異(P<0.05)。結論：超聲對周圍神經慢性卡壓損傷所引起的祌經形態(tài)學變化具有較好的臨床意義，能夠對其損傷做出實時準確的檢查結果，對于臨床治療只有指導性意義?！娟P鍵詞】超聲；周圍神經慢性卡壓損傷：神經形態(tài)學變化【中圖分類號】R2【文獻標號】A【文章編號】2095-7165(2015)16-0020-01Neuralmorphologicalchangesofultrasoundonchronicperipheraln
3、ervedamagecausedbyentrapmentZHANGYun-chu,CHENDing-zhang,WANGWen-ling,GAOLei(DepartmentofUltrasound,TheThirdHospitalofBeijingArmedPoliceCorps,Beijing,100039,China)[Abstract]Objective:Tostudytheultrasoundonchronicperipheralnerveentrapmentnervedamagecausedbymorphologicalchanges.Methods:Tak
4、emonthsExperimentalAnimalCenterhospitalfor10-12months,20rabbitswererandomlydividedinto5groups4,respectively,inthecontrolgroup,2weeksentrapment,entrapment4weeksgroup,entrapmentsixweeksgroupandentrapmenteightweeksgroup.ReferenceMackinnonsotherdesignprogrambuildschronicsciaticnerveentrapme
5、ntmodel,entrapment2weeks,4weeks,6weeksgroup,eightweeksaftersurgerygroupwereintwoweeks,fourweeks,sixweeks,eightweekswhenthesciaticnerveinrabbitsultrasonicobservationandelectrophysiologicalobservation,thecontrolgroupwere8weeksaftertheobservationtime.Results:Withtheextensionoftimecompressi
6、on,sciaticnervethickeningmoreobvious,comparedwiththecontrolgroup,thedifferencewasstatisticallysignificant(P<0.05).Internalechodisorderworsened,andrabbitsMNCV,SNCVspeedslowsdown,andthecontrolgrouphavingdifferencesbetweengroups(P<0.05).Conclusion:Ultrasoundthrowitnervemorphologychan
7、gesofperipheralnervedamagecausedbychronicentrapmenthasbetterclinicalsignificance,tomakereal-timeaccuratetestresultsofitsdamage,theclinicalguidingsignificance.[Keywords]ultrasound;chronicperipheralnerveentrapmentinjury;neuralmorphologicalchanges腕管綜合征、肘管綜合征等疾病是0前臨床上常見的慢性卡壓損傷，外周神經
