資源描述:
《全身麻醉聯(lián)合硬外膜麻醉在直腸癌根治手術(shù)中麻醉療效研究》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫(kù)。
1、全身麻醉聯(lián)合硬外膜麻醉在直腸癌根治手術(shù)中麻醉療效研宄(西南醫(yī)科人學(xué)附屬醫(yī)院麻醉科;四川瀘州646000)【摘要】目的探討全身麻醉聯(lián)合硬膜外麻醉在直腸癌根治術(shù)屮麻醉療效的情況。方法選擇2015年5月至2016年5月期間在我院行手術(shù)治療的84例患考,按照隨機(jī)原則平均分為兩組,對(duì)照組患者實(shí)行全身麻醉,而觀察組患者在全身麻醉基礎(chǔ)上再聯(lián)合硬膜外麻醉,對(duì)兩組患者在不同麻醉模式下的麻醉評(píng)分,在手術(shù)前(tl)、手術(shù)后0.5h(t2)、手術(shù)后lh(t3)、手術(shù)后1.5h(t4)4個(gè)時(shí)間點(diǎn)抽取患者動(dòng)脈血進(jìn)行血?dú)夥治鰧?duì)比PH、PaCO2、PaO2/FiO2等
2、相關(guān)指標(biāo),同時(shí)統(tǒng)計(jì)不良反應(yīng)發(fā)生率。結(jié)果在不良反應(yīng)的發(fā)生率對(duì)比屮,以惡心嘔吐、心動(dòng)過(guò)緩、高血壓、低血壓、心動(dòng)過(guò)速以及室早為主,其屮對(duì)照組發(fā)生率為35.71%(15/42),而觀察組患者則為11.9%(5/42),差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論對(duì)行直腸癌根治術(shù)的患者,采取全身麻醉聯(lián)合硬膜外麻醉的方式能夠更好的保證麻醉療效,在手術(shù)過(guò)程屮能更好的穩(wěn)定患者的生命體征以及氧合功能等,手術(shù)安全性更高?!娟P(guān)鍵詞】全身麻醉;硬外膜麻醉;直腸癌根治手術(shù)Researchontheclinicaleffectofgeneralanesthesiacom
3、binedwithepiduralanesthesiaduringtheradicalresectionofrectalcancerYangXiao-ling(Departmentofanesthesia,theAffiliatedHospitalofMedicalUniversityofSouthwestChina,LuzhouSichuan,646000)[Abstract]Objective:Tostudytheclinicaleffectofgeneralanesthesiacombinedwithepiduralanesthe
4、siaduringtheradicalresectionofrectalcancer.Methods:84patientstreatedfromMay2015toMay2016inourhospitalwereselected.Thesubjectswererandomlyandequallydividedintotwogroups.Thecontrolgroupadoptedthegeneralanesthesia;onthebasis,theobservationgroupalsoadoptedtheepiduralanesthes
5、ia.Theanesthesiaeffectwasanalyzed;beforesurgery(tl),after0.5hofsurgery(t2),afterlhofsurgery(t3)andafter1.5hofsurgery(t4),thearterialbloodwascollectedtoanalyzetheindexofPH,PaCO2andPaO2/FiO2;inaddition,theadverseeventratewascounted.Results:themajoradversereactionsincludedv
6、omiting,nausea,bradycardia,hypertension,hypotension,tachycardiaandventricularprematurebeat;theadverseeventrateforcontrolgroupandobservationgroupwas35.71%(15/42)and11.9%(5/42)(P<0.05).Conclusion:Duringtheradicalresectionofrectalcancer,thegeneralanesthesiacombinedwithepidu
7、ralanesthesiacanguaranteetheclinicaleffect,betterkeepthepatient’svitalsignsandoxygenationfunction,andimprovetheclinicalsafety.[Keywords]generalanesthesia;epiduralanesthesia;radicalresectionofrectalcancer直腸癌是我國(guó)乃至全球常見的消化道惡性腫瘤,0前臨床對(duì)于中早期尚未發(fā)生轉(zhuǎn)移的患者建議采取直腸癌根治術(shù)作為首選的治療方案。然而直
8、腸癌根治術(shù)的實(shí)施就不可避免的會(huì)進(jìn)行麻醉操作,直腸癌患者往往存在明顯的免疫失調(diào)的情況,而麻醉藥物則會(huì)加劇免疫失調(diào)的程度,不利于手術(shù)的順利進(jìn)行,因此對(duì)患者預(yù)后而言是個(gè)很嚴(yán)峻的考驗(yàn)。長(zhǎng)期的臨床實(shí)踐發(fā)現(xiàn),不冋麻醉方