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1、提要目的:探討中藥理氣活血方對(duì)不穩(wěn)定型心絞痛的臨床療效及其作用機(jī)制。方法:從山東中醫(yī)藥大學(xué)附屬醫(yī)院急診科病房和門(mén)診收集符合冠心病不穩(wěn)定型心絞痛診斷標(biāo)準(zhǔn)的患者,將這60例患者,按照隨機(jī)分組的原則,分為2組。對(duì)照組30例,給予常規(guī)西藥治療;治療組30例,在常規(guī)西藥治療的基礎(chǔ)上加服理氣活血方,一日一劑,早晚兩次分服,4周后進(jìn)行臨床療效評(píng)定。分別于治療前后行心電圖及血、尿、大便常規(guī),血流變,血脂以及肝、腎功能等實(shí)驗(yàn)室檢查,對(duì)治療前后患者的臨床癥狀、體征、心電圖及血脂等進(jìn)行綜合分析,從而評(píng)判其療效和安全性。結(jié)果:治療4周
2、后,通過(guò)臨床觀察顯示:治療組在改善患者中醫(yī)證候、提高患者生存質(zhì)量等方面均優(yōu)于對(duì)照組(P<0.01或P<0.05)。結(jié)論:理氣活血方聯(lián)合常規(guī)西藥治療,對(duì)冠心病不穩(wěn)定型心絞痛氣滯血瘀型有顯著療效。關(guān)鍵詞理氣活血方;不穩(wěn)定性心絞痛;臨床研究TheClinicalStudyonTreatingUnstableAnginaPectoriswithLiqiHuoxueDecoctionSpeciality:cardioangiologyofcombinationofTCMandwestmedicineAuthor:Shan
3、gPengTutor:Prof.WuZuoliAbstractObjective:ToinvestigatetheclinicalcurativeeffectandmechanismofLiqiHuoxueDecoctiononunstableanginapectoris.Methods:fromtheAffiliatedHospitalofShandongUniversityofTraditionalChineseMedicineemergencywardandoutpatientcollectionwith
4、unstableanginapectorisofcoronaryheartdiseasediagnosisstandardofpatients,these60patients,accordingtoarandomizedgroupingprinciple,dividedinto2groups.30casesinthecontrolgroupweregivenconventionalwesternmedicinetreatment;,treatmentgroup30cases,inconventionalwest
5、ernmedicinetreatmentbasedontheclothingofregulatingqiandactivatingbloodcirculationmethod,onedayoneagent,andtwotimescentistaken,4weeksaftertheclinicalefficacyevaluation.Respectivelybeforeandafterthetreatmentlineofelectrocardiogramandblood,urine,stool,bloodflow
6、,bloodlipid,hepatic,renalandotherlaboratorytests,beforeandaftertreatmentinpatientswithclinicalsymptoms,signs,electrocardiogramandbloodlipidofcomprehensiveanalysis,andevaluationofitsefficacyandsafety.Results:After4weeks’treatment,throughtheclinicalobservation
7、showed:thetreatmentgroupinimprovingpatientswithsyndromeoftraditionalChinesemedicine,improvepatients'qualityoflifeandotheraspectsarebetterthanthecontrolgroup(P<0.01orP<0.05).Conclusion:ThatcombineLiqiHuoxueDecoctionwithconventionalwesternMedicinetherapy,oncor
8、onaryheartdisease,unstableanginapectorisqistagnationandbloodstasistypehasanotablecurativeeffect.KeywordsLiqiHuoxuedecoction;UnstableAngina;clinicalstudy目錄引言......................................