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1、分類號：R735.2學(xué)校代碼：10392學(xué)科專業(yè)代碼：100104學(xué)號：200902042福建醫(yī)科大學(xué)博士研究生畢業(yè)論文褪黑素抗小鼠胃癌作用及其膜受體機(jī)制研究Inhibitoryeffectofmelatoninonmurinegastriccancerandtherelationshipwithmembranereceptors學(xué)位類型：醫(yī)學(xué)博士所在學(xué)院：基礎(chǔ)醫(yī)學(xué)院研究生：徐麗學(xué)科、專業(yè)：病理學(xué)與病理生理學(xué)導(dǎo)師：周瑞祥教授研究起止日期：2009年9月至2012年3月答辯日期：2012年6月7日二○一二年三月1萬方數(shù)據(jù)2萬方數(shù)據(jù)目錄中文
2、摘要···························································································1英文摘要···························································································3正文引言·············································································
3、····················6第一部分褪黑素體內(nèi)抗小鼠胃癌作用及其對MT1、MT2的影響材料和方法················································································8結(jié)果···························································································17討論······································
4、·····················································27小結(jié)···························································································30第二部分褪黑素體外抗小鼠胃癌細(xì)胞增殖作用及其對MT1、MT2的影響材料和方法·················································································31
5、結(jié)果···························································································39討論···························································································53小結(jié)···············································································
6、············56第三部分MAPKs及PI3K-Akt信號通路在褪黑素抑制小鼠胃癌細(xì)胞增殖中的作用材料和方法中的作用中的作用·············································································PI3-Akt信號通路在褪黑素體內(nèi)外抑制小鼠胃癌細(xì)····57胞增殖中的作用結(jié)果·······················································································
7、····……………………………60討論···························································································65小結(jié)···························································································67結(jié)論······························································
8、··································68參考文獻(xiàn)·······························································
