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1、提要目的:觀察運(yùn)用麥味愈癭合劑干預(yù)心肝陰虛型甲狀腺功能亢進(jìn)癥的臨床療效研究。方法:將60例屬于心肝陰虛型的甲狀腺功能亢進(jìn)癥患者隨機(jī)分為兩組,其中治療組30例,對(duì)照組30例,治療組服用麥味愈癭合劑并配合他巴唑(甲巰咪唑)治療;對(duì)照組僅予以他巴唑(甲巰咪唑)治療,八周為一個(gè)療程,觀察其癥狀體征、甲狀腺腫及甲狀腺功能的變化,進(jìn)行統(tǒng)計(jì)學(xué)意義分析。結(jié)果:經(jīng)臨床觀察研究發(fā)現(xiàn),治療組在改善臨床癥狀方面明顯優(yōu)于對(duì)照組(P<0.05);治療組在改善血清甲狀腺素方面明顯優(yōu)于對(duì)照組(P<0.05);治療組出現(xiàn)肝損害、白細(xì)胞減少等不良反應(yīng)小于對(duì)照組(P<
2、0.05);另外治療組在改善甲亢患者減藥過(guò)程中病情的反復(fù)明顯優(yōu)于對(duì)照組(P<0.05)。結(jié)論:經(jīng)臨床觀察顯示麥味愈癭合劑在治療屬心肝陰虛型甲狀腺功能亢進(jìn)癥具有良好的療效,毒副作用少并且能減少病情反復(fù),值得進(jìn)一步研究。關(guān)鍵詞麥味愈癭合劑;甲狀腺功能亢進(jìn)癥;心肝陰虛型;臨床研究TheClinicalResearchOfHyperthyroidismInHeartAndLiverYinDeficiencyTypeTreatedByMaiweiyuyingmixtureSpecialty:TCM-EndocrinologyAuthor:S
3、hiJilaiTutor:ZhaoQuanlinAbstractObjective:ToobservetheuseofMaiweiyuyingmixtureintreatingofhyperthyroidism.Methods:60casesofhyperthyroidismpatientswererandomlydividedintotwogroups,thetreatmentgroupof30cases,30casesofthecontrolgroup,thetreatmentgrouptoMaiweiyuyinmixture
4、decoctioncombinedwithhisPalestinianmethimazole(methimazole)treatment;thecontrolgrouponlybehemet(methimazole)treatment,eightweeksforacourseoftreatment,observationofthesymptoms,goiterandthyroidfunctionchanges,werestatisticallysignificanceanalysis.Results:theclinicalobse
5、rvationstudyfound,treatmentgroupinimprovingtheserumthyroxinewassignificantlybetterthanthecontrolgroup;liverinjury,leukopeniaandotheradversereactionsthanthoseofthecontrolgroup;inadditiontotheimprovementofclinicalsymptoms(palpitation,sweating,fatigue,hishandsshakingetc.
6、)andreductioninreducingdrugintheprocessofrepeatedillnesswassignificantlybetterthanthecontrolgroup(P<0.05).Conclusion:theclinicalobservationshowedthatMaiweiyuyingmixtureDecoctioninthetreatmentofhyperthyroidismhasgoodcurativeeffect,lesstoxicsideeffectandcanreducerepeate
7、dillness,worthyoffurtherstudy.KeywordsMaiweiyuyingmixture;hyperthyroidism;liveryindeficiency;clinicalobservation目錄引言...............................................................................................................................1臨床研究....................
8、...........................................................................................................2一、研究對(duì)象..........