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1、分類號學號_M200975819__學校代碼___10487____密級碩士學位論文滋養(yǎng)細胞Notch信號通路在子癇前期發(fā)病機制中的研究學位申請人:張娜學位專業(yè):婦產(chǎn)科學指導教師:喬福元教授答辯日期:2012年5月ADissertationSubmittedinPartialFulfillmentoftheRequirementsfortheDegreeofMasterofmedicineResearchonNotchSignalingPathwayofTrophoblastsinPathoge
2、nesisofPreeclampsiaCandidate:ZhangNaSupervisor:Prof.QiaoFuyuanMajor:ObstetricsandGynecologyHuazhongUniversityofScience&TechnologyWuhan,Hubei430074,P.R.ChinaMay,2012獨創(chuàng)性聲明本人鄭重聲明,本學位論文是本人在導師指導下進行的研究工作及取得的研究成果的總結。盡我所知,除文中已經(jīng)標明引用的內容外,本論文不包含任何其他個人或集體已經(jīng)發(fā)表或撰寫
3、過的研究成果。對本文的研究做出貢獻的個人和集體,均已在文中以明確方式標明。本人完全意識到本人將承擔本聲明引起的一切法律后果。學位論文作者簽名:日期:年月日學位論文版權使用授權書本學位論文作者完全了解學校有關保留、使用學位論文的規(guī)定,即:學校有權保留并向國家有關部門或機構送交論文的復印件和電子版,允許論文被查閱和借閱。本人授權華中科技大學可以將本學位論文的全部或部分內容編入有關數(shù)據(jù)庫進行檢索,可以采用影印、縮印或掃描等復制手段保存和匯編本學位論文。保密□,在_____年解密后適用本授權書。本論文屬
4、于不保密□。(請在以上方框內打“√”)學位論文作者簽名:指導教師簽名:日期:年月日日期:年月日目錄英文縮寫及中文對照··························································1中文摘要·········································································2ABSTRACT···············································
5、······················3滋養(yǎng)細胞Notch信號通路在子癇前期發(fā)病機制中的研究前言············································································4材料與方法······································································8結果············································
6、································13討論············································································17參考文獻·········································································19綜述·······················································
7、························21論文缺氧對滋養(yǎng)細胞Notch信號通路的影響·························33致謝···············································································39華中科技大學碩士學位論文英文縮寫及中文對照英文縮寫英文全稱中文全稱PBSphosphatebufferedsaline磷酸鹽緩沖液RT-PCRreversetranscriptase-p
8、olymerasechain逆轉錄聚合酶鏈式反應reactionRT-qPCRreal-timequantitativepolymerasechain實時熒光定量PCRreactionODopticaldensity光密度GAPDHglyceraldehyde-3-phosphatedehydrogenase甘油醛-3-磷酸脫氫酶cDNAcomplementaryDNA互補DNAmRNAmessengerRNA信使RNACTBcytotrophoblast細胞滋養(yǎng)細胞STBsyncytiotro