經(jīng)肝動(dòng)脈灌注不同化療藥物聯(lián)合肝動(dòng)脈栓塞治療中晚期肝細(xì)胞癌的臨床研究

經(jīng)肝動(dòng)脈灌注不同化療藥物聯(lián)合肝動(dòng)脈栓塞治療中晚期肝細(xì)胞癌的臨床研究

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經(jīng)肝動(dòng)脈灌注不同化療藥物聯(lián)合肝動(dòng)脈栓塞治療中晚期肝細(xì)胞癌的臨床研究_第1頁(yè)
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1、授予單位代碼10089學(xué)號(hào)或申請(qǐng)?zhí)?32'13K^(i^ASHebeiMedicalUniversity碩士學(xué)位論文在職科學(xué)學(xué)位經(jīng)肝動(dòng)脈灌注不同化療藥物聯(lián)合肝動(dòng)脈栓塞治療中晚期肝細(xì)胞癌的臨床研究學(xué)位申請(qǐng)人:李淑玲導(dǎo)師:孔麗教授專業(yè):內(nèi)科學(xué)2015年3月河北醫(yī)科大學(xué)學(xué)位論文使用授權(quán)及知識(shí)產(chǎn)權(quán)歸屬承諾本學(xué)位論文在導(dǎo)師(或指導(dǎo)小組)的指導(dǎo)下,由本人獨(dú)立完成。本學(xué)位論文研究所獲得的研究成果,其知識(shí)產(chǎn)權(quán)歸河北醫(yī)科大學(xué)所有。河北醫(yī)科大學(xué)有權(quán)對(duì)本學(xué)位論文進(jìn)行交流、公開(kāi)和使用。凡發(fā)表與學(xué)位論文主要內(nèi)容相關(guān)的論文,第一署名為單位河北醫(yī)科大學(xué),試驗(yàn)材料、原始數(shù)據(jù)、申報(bào)的專

2、利等知識(shí)產(chǎn)權(quán)均歸河北醫(yī)科大學(xué)所有。否則,承擔(dān)相應(yīng)法律責(zé)任。/急大喪/',、,7*一,?、..?fi;.\‘??研究生簽名導(dǎo)師簽章:二級(jí)學(xué)院領(lǐng)導(dǎo)蓋章:m年j月>]:日河北醫(yī)科大學(xué)研究生學(xué)位論文獨(dú)創(chuàng)性聲明本論文是在導(dǎo)師指導(dǎo)下進(jìn)行的研究工作及取得的研究成果,除了文中特別加以標(biāo)注和致謝等內(nèi)容外,文中不包含其他人已經(jīng)發(fā)表或撰寫(xiě)的研究成果,指導(dǎo)教師對(duì)此進(jìn)行了審定。本論文由本人獨(dú)立撰寫(xiě),文責(zé)自負(fù)。研究生簽名:導(dǎo)師簽章:欠年月從日認(rèn)定號(hào):13213河北醫(yī)科大學(xué)在職人員申請(qǐng)碩士學(xué)位論文經(jīng)肝動(dòng)脈灌注不同化療藥物聯(lián)合肝動(dòng)脈栓塞治療中晚期肝細(xì)胞癌的臨床研究研究生姓名:李淑

3、玲二級(jí)學(xué)院:河北醫(yī)科大學(xué)第三醫(yī)院指導(dǎo)教師:孔麗教授申請(qǐng)學(xué)位類別:碩士研究生專業(yè)名稱:內(nèi)科學(xué)起止日期:2012.12-2014.12交稿日期:2015.03目錄中文摘要················································································1英文摘要················································································4英文縮寫(xiě)··························

4、······················································8研究論文經(jīng)肝動(dòng)脈灌注不同化療藥物聯(lián)合肝動(dòng)脈栓塞治療中晚期肝細(xì)胞癌的臨床研究前言················································································9材料與方法·····································································10結(jié)果··························

5、····················································15附圖··············································································19附表··············································································21討論···························································

6、···················27結(jié)論··············································································31參考文獻(xiàn)·······································································32綜述肝癌TACE治療現(xiàn)狀及進(jìn)展………………………………………36致謝·································································

7、···················47個(gè)人簡(jiǎn)歷··············································································48中文摘要經(jīng)肝動(dòng)脈灌注不同化療藥物聯(lián)合肝動(dòng)脈栓塞治療中晚期肝細(xì)胞癌的臨床研究摘要目的:探討不同化療藥物(雷替曲塞、替加氟)行肝動(dòng)脈灌注化療聯(lián)合吡柔比星、奧沙利鉑碘油乳劑肝動(dòng)脈栓塞治療中晚期肝細(xì)胞癌的臨床療效及安全性,為臨床治療中晚期肝細(xì)胞癌提供實(shí)踐依據(jù)和理論依據(jù)。方法:研究對(duì)象選取河北大學(xué)附屬醫(yī)院2011年12月-2014年1月確診的89例肝細(xì)胞癌

8、患者,診斷符合2011年中國(guó)抗癌協(xié)會(huì)肝癌專業(yè)委員會(huì)修訂的肝癌臨床診斷標(biāo)準(zhǔn)。所有患者均經(jīng)臨床癥狀

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