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1、遼寧中醫(yī)雜志2014年第41卷第1期·113·DOI∶10.13192/j.issn.1000-1719.2014.01.049中藥聯(lián)合貝那普利治療糖尿病腎病臨床療效1,2葛靜(1.南京中醫(yī)藥大學(xué),江蘇南京210046;2.江蘇省中醫(yī)院,江蘇南京210029)摘要:目的:探討中藥聯(lián)合貝那普利治療糖尿病腎病的臨床效果。方法:選擇該院收治的128例糖尿病腎病患者的臨床資料,其中,觀察組64例患者采用中藥聯(lián)合貝那普利治療,而對(duì)照組64例患者采用貝那普利治療,比較兩組患者2的臨床效果。結(jié)果:治療后,觀察組患者的總有效率為93.75%,明顯高于
2、對(duì)照組患者,且差異具有統(tǒng)計(jì)學(xué)意義(χ=4.23,P<0.05),觀察組患者的24hUMA、SCr、CCr等指標(biāo)均較對(duì)照組患者出現(xiàn)了明顯改善,組間比較,差異具有統(tǒng)計(jì)學(xué)意義(P<0.05),觀察組與對(duì)照組患者的血糖指標(biāo)和血壓指標(biāo)均較治療前出現(xiàn)了明顯的改善,且組內(nèi)比較,差異具有統(tǒng)計(jì)學(xué)意義(P<0.05),兩組不良反應(yīng)發(fā)生率相當(dāng),差異無(wú)統(tǒng)計(jì)學(xué)意義。結(jié)論:金芪降糖片與西藥聯(lián)合治療糖尿病腎病可明顯改善患者的臨床癥狀,有利于患者病情的恢復(fù),值得臨床應(yīng)用。關(guān)鍵詞:中藥;貝那普利;糖尿病腎病;臨床效果中圖分類(lèi)號(hào):R697文獻(xiàn)標(biāo)志碼:B文章編號(hào):1000
3、-1719(2014)01-0113-03ClinicalAnalysisofTraditionalChineseMedicineCombinedwithBenazeprilforTreatmentofDiabeticNephropathy1,2GEJing(1.NanjingUniversityofChineseMedicine,Nanjing210046,Jiangsu,China;2.JiangsuProvincialHospitalofTCM,Nanjing210029,Jiangsu,China)Abstract:Objec
4、tive:ToexploretheclinicalefficacyoftraditionalChinesemedicinecombinedwithbenazeprilfortreatmentofdiabeticnephropathy.Methods:128caseswithdiabeticnephropathyinourhospitalweredividedintotwogroups,includingtheob-servationgroupof64caseswithtraditionalChinesemedicinecombined
5、withbenazepriltherapy,andthecontrolgroupof64pa-tientstreatedwithbenazepril.Results:Aftertreatment,theoveralleffectiverateofobservationgroupwas93.75%,significantly2higherthanthatofthecontrolpatients,andthedifferencewasstatisticallysignificant(χ=4.23,P<0.05),observationgr
6、oup's24hUMA,SCr,CCrotherindicatorshadsignificantimprovementthanthoseofthecontrolgroup,andthedifferencewasstatistical-lysignificant(P<0.05).Theobservationgroupandthecontrolgrouppatients'bloodsugarlevelandbloodpressuretargetshadimprovementthanthosebeforetreatment,andthedi
7、fferencewasstatisticallysignificant(P<0.05).Therewasaconsiderablein-cidenceofadversereactionsinbothgroups,andthedifferencewasnotstatisticallysignificant.Conclusion:TraditionalChinesemedicinecombinedwithbenazeprilfortreatmentofdiabeticnephropathycansignificantlyimproveth
8、etreatmentofdiabeticne-phropathy,anditisconducivetotherecoveryofthepatients'condition.Keywords:Chinesemedicine