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1、第18卷第5期遼寧中醫(yī)藥大學學報Vol.18No.52016年5月JOURNALOFLIAONINGUNIVERSITYOFTCMMay,2016DOI:10.13194/j.issn.1673-842x.2016.05.069補腎疏肝湯治療腎虛肝郁型更年期綜合征臨床療效觀察郭彥(遼寧中醫(yī)藥大學附屬第四醫(yī)院,遼寧沈陽110101)摘要:目的:探究補腎疏肝湯治療腎虛肝郁型更年期綜合征的臨床療效。方法:選取我院婦產(chǎn)科收治的腎虛肝郁型更年期綜合征患者76例,采用隨機數(shù)字表隨機分為2組,每組38例患者,其中對照組38
2、例,給予鹽酸帕羅西汀片進行治療,2周為1個療程,治療3個療程;實驗組38例,給予自擬補腎疏肝湯進行治療,2周為1個療程,治療3個療程。治療結(jié)束后,對比患者的臨床療效及抑郁癥狀評分,對比患者雌激素水平。結(jié)果:①治療后兩組患者各臨床癥狀比較,實驗組較對照組改善明顯,檢測臨床總有效率可知,實驗組臨床總有效率為89.5%,對照組臨床總有效率為78.9%,兩組結(jié)果差異有統(tǒng)計學意義(P<0.05);②治療結(jié)束后,兩組患者抑郁癥狀評分顯示,實驗組較對照組有明顯減少,兩組結(jié)果差異有統(tǒng)計學意義(P<0.05);③治療結(jié)束后,檢
3、測患者E2、FSH、LH等激素水平,結(jié)果顯示E2水平有明顯上升,F(xiàn)SH及LH水平有明顯下降,實驗組各指標變化較對照組明顯,兩組結(jié)果差異有統(tǒng)計學意義(P<0.05)。結(jié)論:補腎疏肝湯可通過調(diào)節(jié)患者體質(zhì),改善腎氣不足、肝氣郁滯之癥,可調(diào)節(jié)患者體內(nèi)雌性激素水平,緩解患者抑郁情緒,有效治療腎虛肝郁型更年期綜合征,值得臨床推廣。關鍵詞:補腎疏肝湯;腎虛肝郁型;更年期綜合征;臨床療效中圖分類號:R588文獻標志碼:A文章編號:1673-842X(2016)05-0209-04TonifingKidneySoothingL
4、iverDecoctionTreatmentKidneyLiverDepressionTypeoftheClinicalEffectoftheTreatmentofMenopausalSyndromeGUOYan(TheFourthAffiliatedHospitalofLiaoningUniversityofTraditionalChineseMedicine,Shenyang110101,Liaoning,China)Abstract:Objective:Toexplorethetonifingkidne
5、ysoothingliverdecoctiontreatmenttheclinicalcurativeeffectofkidneyliverdepressiontypeofmenopausesyndrome.Methods:Ourhospitalforkidneyliverdepressionpatientswithclimactericsyndromeof76caseswithrandomnumbertablewererandomlydividedintotwogroups,eachgroupof38cas
6、es,controlgroupinwhich38cases,giveparoxetinehydrochloridetreatment,2weeksforaperiodoftreatment,thetreatmentof3courses;experimentalgroup38cases,givetonifingkidneysoothingliverdecoctiontreatment,2weeksforaperiodoftreatment,treatment3periodoftreatment.Aftertre
7、atment,thecontrastofthepatient'sclinicalcurativeeffectanddepressionsymptomscores,comparedtopatientswithestrogenlevels.Results:(1)Inthetwogroupsaftertreatmentinpatientswiththeclinicalsymptomswereimproved,detectionofclinicalcurativeeffect,clinicaltotaleffecti
8、veratewas89.5%,whilethecontrolgrouptotaleffectiveratewas78.9%,theresultsaresimilarbetweenthetwogroupshavestatisticalsignificance(P<0.05);(2)Inthetwogroupsaftertreatmentinpatientswithdepressivesymptomss