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《30t磁共振擴散加權(quán)成像應(yīng)用于腎臟實質(zhì)性腫瘤診斷及鑒別診斷的初步研究》由會員上傳分享,免費在線閱讀,更多相關(guān)內(nèi)容在工程資料-天天文庫。
1、UndertheCurve,ROC),曲線下面積為0.877,以1.27X10W7s為閾值,敏感度為78.3%,特異性為75%。(2)透明細胞癌高級別組腫瘤的平均ADC值(1.46±0.17XWW/S)低于低級別組腫瘤的平均ADC值(1.94土0.08X10_W/s),(pv0?05)。以透明細胞癌高低級別繪制ROC曲線,曲線下面積為0.808,以1.23X10_W/s為閾值,敏感度為90.5%,特異性為71.4%。(3)腫瘤、瘤旁腎實質(zhì)及對側(cè)正常腎實質(zhì)組:組內(nèi)比較:1)良性腫瘤的ADC值(0.93±0.12X10W/s)分別小于對側(cè)正常腎
2、實質(zhì)的ADC值(2.12±0.05X10_3mm2/s)及對側(cè)瘤旁腎實質(zhì)的ADC值(2?10土0.03X10W/s)(pv0.05),差異有統(tǒng)計學(xué)意義;2)良性腫瘤瘤旁腎實質(zhì)與對側(cè)正常腎皮質(zhì)的ADC值差異無統(tǒng)計學(xué)意義(p>0.05)。3)惡性腫瘤的ADC值(1.72±0.09X10_W/s)分別小于對側(cè)正常腎實質(zhì)的ADC值(2.11土0.03X10_W/s)及對側(cè)瘤旁腎實質(zhì)的ADC值(2.01±0.03X10_3mm2/s),(p<0.05);4)惡性腫瘤瘤旁腎實質(zhì)(2.01±0.03X10ini『/s)小于對側(cè)正常腎皮質(zhì)的ADC值(2.l
3、l±0?03Xl(TW/s)(p<0.05),差異有統(tǒng)計學(xué)意義。組間比較:采用Mann-WhitneyU檢驗比較良性瘤旁與惡性瘤旁的ADC值、良性對側(cè)腎實質(zhì)與惡性對側(cè)腎實質(zhì)的ADC值及良性對側(cè)腎實質(zhì)、惡性對側(cè)腎實質(zhì)與志愿者腎實質(zhì)的ADC值,差異無統(tǒng)計學(xué)意義。結(jié)論:磁共振彌散加權(quán)成像可用于腎臟良惡性腫瘤的定性診斷。ADC值可用于腎臟良惡性腫瘤及腎透明細胞癌不同級別的鑒別診斷。ADC值對觀察腎臟惡性腫瘤對瘤旁腎實質(zhì)的影響有一定價值。關(guān)鍵詞:腎臟腫瘤,磁共振檢查,擴散加權(quán)成像,表觀擴散系數(shù)AbstractObjective:Tostudythed
4、iagnosticutilityofMagneticResonanceDiffusionweightedimaging(MRDWI)indifferentiatingrenalturno匚Toevaluatetheidentifiedvalueofapparentdiffusioncoefficient(ADC)indifferentiatingbenignfromthemalignantrenaltumors.differentiatingvariouspathologicgradesofrenalclearcellcarcinoma,a
5、ndanalyzingtheeffecttherenaltumorhadonperitumoralrenalparenchyma?MaterialsandMethods:35patientsand5healthyvolunteersunderwent3.0TconventionalMRIscanninganddiffusionweightedimagingscanningbeforesurgicaloperation.AllthepatientswereSurgicalandpathologicaldiagnosed.Amongthepat
6、ientswere16malesand19females(Age:21-72,Averagingage:48).5volunteersincluded3malesand2females(Age:22-41,Averagingage:31).DWIwereobtainedwithbvaluesof0,400and600s/mm2.Bytwoexperiencedradiologistsblindedreadingandanalyzeddata.UsingworkSyngoworkstationFoncToolsoftwareforDWIdat
7、apost-processing.ROI(regionofinterest)wasasfaraspossiblebigandatthesamesize.ROIplacedintheessenceofthetumor,peritumoralrenalparenchymaandthecontralateralnormalkidneyarea.Byusingintraclasscorrelationcoefficient(ICC)andthenonparametrictestinthestatisticalsoftwareSPSS19.0toan
8、alyzeandstatisticstheconsistencyofthetwoADCvaluesandthedataofeachgroup.Result:35lesionsin