復(fù)合振動(dòng)儀治療骨質(zhì)疏松對(duì)骨代謝影響臨床觀察

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1、復(fù)合振動(dòng)儀治療骨質(zhì)疏松對(duì)骨代謝影響臨床觀察作者：鄭錦暢陳建庭裴衛(wèi)衛(wèi)【摘要】目的觀察復(fù)合振動(dòng)儀治療骨質(zhì)疏松(0P)對(duì)骨代謝的影響。方法70例OP志愿者隨機(jī)分成復(fù)合振動(dòng)組和對(duì)照組，每組35例。復(fù)合振動(dòng)組采用自行研制的復(fù)合振動(dòng)儀進(jìn)行全身振動(dòng)治療，振動(dòng)頻率45?55Hz,振動(dòng)強(qiáng)度0.5?0.8g,1次/隔天，30min/次，連續(xù)3個(gè)月，對(duì)照組不進(jìn)行任何干預(yù)，于試驗(yàn)開(kāi)始前3天、試驗(yàn)后第1、3個(gè)月分別檢測(cè)各組堿性磷酸酶(ALP)、骨鈣素(0C)、抗酒石酸酸性磷酸酶(TRAP)、鈣磷乘積(〔Ca)X(P〕)的變化。結(jié)果第3個(gè)月，復(fù)合振動(dòng)組

2、的ALP、OC、TRAP、(Ca〕X(P〕分別比試驗(yàn)前增加了44.6%、-9.4%、1.7%、7.5%,對(duì)照組的相應(yīng)指標(biāo)分別比試驗(yàn)前增加了22.8%、T3.3%、3.6%、4.7%,P值分別為0.108、0.788、0.606、0.171。結(jié)論復(fù)合振動(dòng)儀治療0P對(duì)骨代謝的影響無(wú)統(tǒng)計(jì)學(xué)意義，但骨代謝的絕對(duì)值有變化?！娟P(guān)鍵詞】復(fù)合振動(dòng)；骨質(zhì)疏松;堿性磷酸酶；骨鈣素；抗酒石酸酸性磷酸酶;鈣磷乘積Clinicalobservationofbonemetabolisminosteoporosispatientstreatedwithc

3、ompoundvibra.tionmachineZHENGJinChang,CHENJianTing,PEIWeiWei.DepartmentofOrthopaedicSurgeryandSpine,NanfangHospital,SouthernMedicalUniversity,Guangzhou510515,Guangdong,China[Abstract]ObjectiveToobservetheeffectofbonemetabolisminosteoporosis(OP)patientstreatedwithco

4、mpoundvibrationmachine?Methods70OPvolunteerswereselectedandwererandomlydividedintowholebodycompoundvibrationtraininggroup(WBCV,n二35)andcontrolgroup(CON,n=35)?ThepatientsinWBCVgrouptreatedwith3monthwholebodycompoundvibration(30min/d,1time/qd,oscillationfrequency45?5

5、5Hz,intensityofvibration0.5?0.8g).ThepatientsinCONgroupweren'tgivenanytreatment,didnotparticipateinanytraining,justkeepingthenormallifeasbefore?Alkalinephosphatase(ALP),osteocalcin(0C),tartrateresistanceacidphosphatase(TRAP)andcalciumphosphorusproductweremeasuredon

6、3daysbeforeexperiment,1and3monthsafterexperiment?ResultsThelevelofALP,0C,TRAP,(Ca)X(P)inWBCVgroupwasincreasedby44.6%,一9?4%,1.7%and7.5%respectively.However,itwasincreaseby22.8%,-13.3%,3.6%and4.7%respectivelyinCONgroup(P=0.108,0.788,0.606and0.171).ConclusionsThewhole

7、bodycompoundvibrationtraininghasnoeffectonbonemetabolisminOP,whiletheabsolutevalueofbonemetabolismhasbeenchanged.[Keywords】Compoundvibration；Osteoporosis；Alkalinephosphatase(ALP)；Osteocalcin(0C)；Tartrateresistanceacidphosphatase(TRAP)；Calciumphosphorusproduct(〔Ca〕X

8、〔P〕)骨質(zhì)疏松(0P)及0P性骨折是危害中老年健康的常見(jiàn)病,尤以絕經(jīng)后婦女為甚。臨床上常采用藥物治療抑制骨吸收或者促進(jìn)骨形成，但藥物大多存在副作用。近年來(lái)物理療法(力學(xué)、電磁學(xué))防治0P的研究成為熱點(diǎn)(1?4〕。低于引起骨組織損傷的機(jī)械振動(dòng)信號(hào)具有很強(qiáng)的成骨效應(yīng)，是一種新型治療0P的模式