冠狀病毒Coronavirusl論文-2015 High prevalence of common respiratory viruses and no evidence of Middle East Respiratory Syndrome Coronavirus in Ha.pdf

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1、ArticleType:OriginalarticleHighprevalenceofcommonrespiratoryvirusesandnoevidenceofMiddleEastRespiratorySyn-dromeCoronavirusinHajjpilgrimsreturningtoGhana,201311111AugustinaAnnan,MichaelOwusu,KwadwoSarfoMarfo,RichardLarbi,FranciscaNaanaSarpong,2345,61YawAdu-Sarkodie,JosephA

2、mankwa,SamuelFiafemetsi,ChristianDrosten,EllisOwusu-Dabo,5IsabellaEckerle1KumasiCentreforCollaborativeResearchinTropicalMedicine,KwameNkrumahUniversityofSci-enceandTechnology,Kumasi,Ghana2DepartmentofClinicalMicrobiology,KwameNkrumahUniversityofScienceandTechnology,Ku-masi

3、,Ghana3ArticlePublicHealthDivision,GhanaHealthServices,Accra,Ghana4PortHealthDivision,GhanaHealthServices,Accra,Ghana5InstituteofVirology,UniversityofBonnMedicalCentre,Bonn,Germany6GermanCentreforInfectionResearchAbstractObjective:TheMiddleEastrespiratorysyndromecoronaviru

4、s(MERS-CoV)emergedin2012ontheArabianPeninsulaandhascausedsevererespiratorydiseasewithmorethan800laboratory-confirmedcases.ThereturnofinfectedpilgrimstotheirhomecountrieswithaputativespreadofMERS-CoVnecessitatesfurthersurveillance.Methods:Asurveillancestudyof839adultAfrican

5、HajjpilgrimsreturningtoAccrainGhana,WestAfrica,wasconductedin2013toassesstheprevalenceofrespiratorysymptomsaswellasofMERS-CoV,humanRhinovirus(HRV),RespiratorySyncytialVirus(RSV),andInfluenzaAvirus(FLUA)infec-tion.Results:651(77.6%)pilgrimshadrespiratorysymptoms.Testswerepo

6、sitiveforatleastoneofthevirusesotherthanMERS-CoVin179(21.3%)ofallpilgrims,with22.4%detectioninsymptomaticvs.17.6%detectioninasymptomaticpilgrims.NoMERS-CoVwasdetected,althoughcommonrespira-toryviruseswereprevalent,withpositivefindingsforHRVin141individuals(16.8%),RSVin43in

7、di-Thisarticlehasbeenacceptedforpublicationandundergonefullpeerreviewbuthasnotbeenthroughthecopyediting,typesetting,paginationandproofreadingprocess,whichmayAcceptedleadtodifferencesbetweenthisversionandtheVersionofRecord.Pleasecitethisarticleasdoi:10.1111/tmi.12482Thisart

8、icleisprotectedbycopyright.Allrightsreserved.viduals(5.1%),andFLUAin11individuals(1.3%).R