資源描述:
《伴海馬硬化的顳葉癲癇患者的臨床特點分析》由會員上傳分享,免費在線閱讀,更多相關內容在學術論文-天天文庫。
1、腦與神經(jīng)疾病雜志2013年第21卷第6期401·論著·伴海馬硬化的顳葉癲癇患者的臨床特點分析楊防胡靜澤張志強林穎馮婷戴加飛李敏李華陳光輝劉玲【摘要】目的通過比較伴和不伴海馬硬化的顳葉癲癇患者的臨床特點,為臨床診治提供依據(jù)。方法收集2009年6月至2012年6月期間南京軍區(qū)南京總醫(yī)院顳葉癲癇患者144例,通過頭顱MRI或顳葉癲癇手術病理分類,對每位患者發(fā)作時臨床表現(xiàn)、發(fā)作問期、起病年齡及腦電圖等進行分析。結果伴海馬硬化的顳葉癲癇患者起病年齡較不伴海馬硬化的顳葉癲癇患者更小,同時更易出現(xiàn)發(fā)作前先兆和意識障礙。伴或不伴海馬硬化的顳葉癲癇患者的腦電圖異常率相似,大多數(shù)患者腦電圖可發(fā)現(xiàn)癲癇樣
2、異常改變。海馬硬化患者有高熱驚厥史的更常見。結論伴有海馬硬化的顳葉癲癇患者有一些特殊的臨床表現(xiàn),深入了解伴海馬硬化的顳葉癲癇患者的臨床特點將利于更好更快地選擇顳葉癲癇患者的合理治療方案?!娟P鍵詞】海馬硬化;顳葉癲癇;腦電圖;高熱驚厥中圖分類號:R742.1文獻標識碼:A文章編號:1006.351X(2013)06—0401—03ThecharacteristicsoftemporallobeepilepsywithhippocampalsclerosisYANGFang,HUJing-ze,ZHANGZhi—qiang,LINYin,F(xiàn)ENGTing,DAIJia,12Min,Ll
3、Hua,CHENGuang—hui,LIU丘ng.DepartmentofNeurology,theGeneralHospital,NanfingUniversitySchoolofMedicine,Jiangsu210002,ChinaCorrespondingauthor:LIU幻,Email:liuling8210@126.COrn【Abstract】ObjectiveToinvestigatecharacteristicsoftemporallobeepilepsy,thecomparisonofclinicalcharacteristicswithandwithouthi
4、ppocampalsclerosisinpatientswithtemporallobeepilepsywereevaluated.MethodAretrospectivestudywasconductedbyanalyzingclinical,lifestyledata,andinterictalEEGcollectedfrom144patientswithtemporallobeepilepsybetweenJune2009toJune2012.ResultOnsetageinpatientswithtemporallobeepilepsyassociatedwithhippo
5、campalsclerosiswassmallerthanwithouthippocampalsclerosis,andauraanddisturbanceofconsciousnessweremorecommon.TheEEGabnormalratewas70.14%,buttherewasnodifferenceintheEEGabnormalratebetweenpatientswithorwithouthippocampalsclerosis.Patientswithhippoeampalsclerosisweresignificantlyassociatedwithfeb
6、rileseizures.ConclusionThisretrospectivestudysuggeststhatsomespecialclinicalmanifestationsassociatedwithpatientswithhippoeampalsclerosis.In—depthunderstandingofclinicalcharacteristicsassociatedwithpatientswithhippocampalsclerosiswillfavorthereasonablediagnosisandtreatmentofpatientswithtemporal
7、lobeepilepsy.【Keywords】Hippocampalsclerosis;Temporallobeepilepsy;EEG;Febrileconvulsion癲癇是常見的一種病因復雜的反復發(fā)作的神經(jīng)系月頭顱MRI或手術病理確診的連續(xù)78例伴海馬硬化的統(tǒng)疾病,其發(fā)病率為0.5%~1%。海馬硬化被認為是癲顳葉癲癇患者和頭顱MRI和手術病理未發(fā)現(xiàn)海馬硬化癇特別是顳葉癲癇的重要病理改變。顳葉癲癇占藥物的連續(xù)66例顳葉癲癇患者的臨床特點。難治性癲癇的60%一80%