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《莫西沙星聯(lián)合哌拉西林鈉他唑巴坦鈉治療重癥肺炎臨床療效觀察.doc》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在工程資料-天天文庫(kù)。
1、莫西沙星聯(lián)合哌拉西林鈉他睦巴坦鈉治療重癥肺炎臨床療效觀察［摘要］目的觀察莫西沙星聯(lián)合哌拉西林鈉他哇巴坦鈉治療重癥肺炎臨床療效。方法選取2010年2月?2012年2月在我院治療的重癥肺炎患者80例隨機(jī)分為兩組。治療組給予靜脈滴注莫西沙星400mg/d加哌拉西林鈉他哇巴坦鈉13.5g/d,對(duì)照組給予靜脈滴注左氧氟沙星400mg/d加哌拉西林鈉他哩巴坦鈉13.5g/d,兩組使用相同常規(guī)治療主要為機(jī)械通氣、祛痰、解痙等視病情給予強(qiáng)心、利尿等對(duì)癥及氨基酸、白蛋白等支持治療，兩組均治療10?14d觀察療效。結(jié)果治療組在發(fā)熱消失、痰液顏色改變、血常規(guī)恢
2、復(fù)正常、機(jī)械通氣、胸部影像明顯吸收方面改善所需要的時(shí)間相比對(duì)照組短，差異有統(tǒng)計(jì)學(xué)意義；治療組在白細(xì)胞、血?dú)狻⒏文I功能指標(biāo)顯著好于對(duì)照組；治療組的總有效率明顯優(yōu)于對(duì)照組。結(jié)論莫西沙星聯(lián)合哌拉西林鈉他哇巴坦鈉治療重癥肺炎療效顯著，值得臨床推廣。［關(guān)鍵詞］莫西沙星；哌拉西林鈉他11坐巴坦鈉；重癥肺炎［中圖分類號(hào)］R969.4；R563.1［文獻(xiàn)標(biāo)識(shí)碼］B［文章編號(hào)］1673—9701(2012)26—0066—02Clinicalobservationofseverepneumoniatreatedwithmoxifloxacinhydroch
3、loridecombinedwithpiperacillinsodiumandtazobactamsodiumforinjectionXIAOXiaorongICU,theFirstPeople，sHospitalofTaizhouCityinZhejiangProvince,Taizhou318020,China[Abstract]ObjectiveToevaluatetheclinicaleffectofmoxifloxacinhydrochloridecombinedwithpiperacillinsodiumandtazobact
4、ainsodiumforinjectiontreatmentonseverepneumonia?MethodsSelected80severepneumoniapatientstreatedinourhospitalfromFebruary2010toFebruary2012divideinto2groupsrandomly.ThetreatmentgroupwasprovidedwithintravenousdripMoxifloxacin400mg/dandTazobactamSodium/Piperaci11inSodium13.5
5、g/d.ThecontrolgroupwasprovidedwithintravenousdripLevofloxacin400mg/dandTazobactamSodium/Piperaci11inSodium13.5g/d?Bothgroupswereprovidedwiththesameconventionaltreatment，mainlyincludingmechanicalventilation,eliminatingphlegmandspasmolysis,etc.,andsymptomatictreatmentsuchas
6、cardiacanddiuresisandsupportingtherapysuchasaminoacidandalbumin.Thecurativeeffectsinbothgroupswereobservedafter10一14daystreatment?ResultsAftertreatment,thetimeforthetreatmentgrouptoimproveinfiveaspectssuchasfeverdisappearance,sputumcolorchange,bloodroutinereturningtonorma
7、l，mechanicalventilationandobviousabsorptionofchestimagingisshorterthanthatforthecontrolgroup,whichhadasignificantdifference；aftertreatment,leukocyte，bloodgasandhepatorenalfunctionalindexesofthetreatmentgroupwereparticularlybetterthanthoseofthecontrolgroup；theoveralleffici
8、encyofthetreatmentgroupwasobviouslyhigherthanthatofthecontrolgroup.ConclusionMoxifloxacinhydroch
