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1、·472·中國感染控制雜志2014年8月第13卷第8期ChinJInfectControlVol13No8Aug2()14DOI:10.3969/j.issn.1671-9638.2014.08.006.論著.ICU導管相關(guān)血流感染危險因素分析劉銀梅,余紅,楊惠英(上海市第十人民醫(yī)院院內(nèi)感染與疾病控制處,上海200072)[摘要]目的了解重癥監(jiān)護室(ICU)導管相關(guān)血流感染(CRBSI)的危險因素,為其預防控制提供科學依據(jù)。方法選取2008年1月~2()12年12月某院ICU行中心靜脈置管(CVC)且時間>48h的住院患
2、者1677例,分為CRBSI組和非CRBSI組,對其進行危險因素分析。結(jié)果CVC使用率為92.88(21041d);發(fā)生CRBS186例,CRBS1發(fā)生率為5.13,千導管日CRBSI發(fā)生率為4.02/1000,CRBSI組患者病死率為58.14(50/86),顯著高于非CRBSI組的36.83(586/1591),差異有統(tǒng)計學意義(=15.74,P5d、CVC時間>5d、CVC次數(shù)>1次是CRBSI的危險因素(均P<().O1)。結(jié)論了解ICU住院患
3、者CRBSI狀況及其危險因素,可為進一步開展目標性監(jiān)測,實現(xiàn)CRBSI“零寬容”的奮斗目標提供參考。[關(guān)鍵詞]導管相關(guān)血流感染;危險因素;logistic回歸分析;醫(yī)院感染;重癥監(jiān)護室[中圖分類號]R181.32[文獻標識碼]A[文章編號]1671—9638(2014)08—0472—04Riskfactorsforcatheter—relatedbloodstreaminfectioninanintensivecareunitL己,Y/n—mei,yUHong,YANGHui—ying(ShanghaiTenthPeo
4、ple’sHospital,Shanghai200072,China)[Abstract]ObjectiveTostudytheriskfactorsforcatheter-relatedbloodstreaminfection(CRBSI)inanintensivecareunit(ICU),andprovidescientificevidenceforCRBSIpreventionandcontro1.Methods1677ICUpatientswithcentralvenouscatheterization(CVC
5、)for>48hoursbetweenJanuary2008andDecember2012weredividedin—toCRBSIgroupandnon-CRBSIgroup,riskfactorsforCRBS1wereanalyzed.ResultsTheutilizationrateofCVCwas92.88%(21041d);86(5.13%)patientsdevelopedCRBSI,theincidenceofCRBSIper1000catheterization-daywas4.02,themortal
6、ityofCRBSIgroupwassignificantlyhigherthannon-CRBSIgroup(58.14%[50/86]vs36.83G[586/1591])(=15.74,P%0.01).MultivariatelogisticregressionanalysisshowedthattheriskfactorsforCRBSIin—cludedlengthofstayinICU>5days,CVC>5days,theepisodeofCVC>1(P<0.O1).ConclusionRealizingt
7、heoccur—rencestatusandriskfactorsofCRBSIinICUpatientscanprovidereferenceforfurthertargetedmonitorandimplementationofzerotolerancegoaloftheCRBSI.[Keywords]catheter-relatedbloodstreaminfection;riskfactor;logisticregressionanalysis;heahhcareassociatedinfection;inten
8、sivecareunit[ChinInfectControl。2014,13(8):472—474,485]隨著中心靜脈置管(centralvenouscatheteriza—導致患者住院時間延長,醫(yī)療費用增加,預后不良以tion,CVC)技術(shù)在臨床上的廣泛應用,由CVC引發(fā)及生存質(zhì)量下降等。本院采用集束化干預策略對