健脾化瘀中藥治療肝癌臨床研究-論文.pdf

《健脾化瘀中藥治療肝癌臨床研究-論文.pdf》由會(huì)員上傳分享，免費(fèi)在線(xiàn)閱讀，更多相關(guān)內(nèi)容在應(yīng)用文檔-天天文庫(kù)。

1、新中醫(yī)2013年12月第45卷第12期JOURNALOFNEWCHINESEMEDICINEDecember2013Vo1．45No．12·129·健脾化瘀中藥治療肝癌臨床研究鐘崇’，李惠東’，陳智遠(yuǎn)2，郭榮平21．廣州中醫(yī)藥大學(xué)第一附屬醫(yī)院肝膽外科，廣東廣州5104052．中山大學(xué)腫瘤防治中心肝膽外科，廣東廣州510061[摘要]目的：觀(guān)察手術(shù)并健脾化瘀中藥治療肝癌的臨床療：故。方法：將120例患者隨機(jī)分為2組各6O例，治療組采用手術(shù)并健脾化瘀法中藥治療，對(duì)照組采用手術(shù)治療，觀(guān)察治療周期為1年，以無(wú)瘤生存率和生存率作為主要評(píng)價(jià)指標(biāo)分析療效。結(jié)果：至隨訪(fǎng)結(jié)束，復(fù)發(fā)率治組為8

2、0．0％，對(duì)照組為93．3％，2組比較，差異有顯著性意義(P

3、[文獻(xiàn)標(biāo)識(shí)碼]A[文章編號(hào)_】0256—7415(2013)12一O129—04ClinicalStudyofChineseHerbswithActionsofInvigoratingSpleenandRemovingBloodStasisinTreatingHepat0ce¨uIarCarcinomaZHONGChong，LIHuidong，CHENZhiyuan，etalAbstract：Objective：ToinvestigatetheclinicaleffectofqepatectomycombinedwithChineseherbswiththeactionso

4、finvigoratingspleenandremovingbloodstasisforthetreatmentofhepatocellularcarci-nomafHCC)．Methods：OnehundredandtwentyHCCpatientswererandomizedintotreatmentgroup(n=60)andcontrolgroup(n=60)．Bothgroupreceivedhepatectomy．ThetreatmentgroupreceivedChinesemedicinaltherapy0finvigoratingspleenandremo

5、vingbloodstasisasadjuvanttreatmentaftersurgery．Theobservationtimelastedoneyear．Tumor—freesurvivalrate(TFoR)andoverallsurvivalrate(OSR)wereob—servedtoevaluatethetherapeuticeffect．Results：Attheend3ffollow—up，therecurrenceratewas80％inthetreatmentgroupandwas93．3％inthecontrolgroup，thedifference

6、beingsignificant(P<0．O5)．Inthetreatmentgroup，TFSRfor1，3and5year(s)was4．8％，29．6％，14．1％respectively，andtheme—diantumor—freetimewas22months；inthecontrolgroup，theTFSRfor1，3and5year(s)was71．7％，23．3％，4．8％，respectively，andmediantumor-freetimewas15months，thedifferencebeingsignifi—cantinthetwogroup

7、s(P<0．05)．Theone-．3一and5一yearsurvivalratesandmediansurvivaItimewere96．7％，64．4％，40．1％and49monthsinthetreatmentgroup，andwere93．3％，62．9％，31．9％and44monthsinthecontrolgrouprespectively，thedifferencebeingsignificant(P<0．05)．Conclusion：Thehep—atectomycombinedwithChin