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《氟芬那酸丁酯軟膏封包聯(lián)合復(fù)方倍他米松局部注射治療結(jié)節(jié)性癢疹療效觀察》由會員上傳分享,免費在線閱讀,更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫。
1、氟芬那酸丁酯軟膏封包聯(lián)合復(fù)方倍他米松局部注射治療結(jié)節(jié)性癢疹療效觀察【摘要】目的觀察氟芬那酸丁酯軟膏封包聯(lián)合復(fù)方倍他米松局部注射治療結(jié)節(jié)性癢疹的臨床療效。方法100例結(jié)節(jié)性癢疹患者隨機(jī)分為治療組和對照組,各50例。治療組采用氟芬那酸丁酯軟膏封包聯(lián)合復(fù)方倍他米松局部注射治療;對照組僅采用復(fù)方倍他米松局部注射治療。對比兩組療效。結(jié)果兩組治療2周末,治療組總有效率為98%,對照組總有效率為80%,兩組比較,差異具有統(tǒng)計學(xué)意義(x2=8.27,P【關(guān)鍵詞】氟芬那酸丁酯;復(fù)方倍他米松;封包;注射;結(jié)節(jié)性癢疹DOI:10.14163/j.cnki.ll-5547/r.2015.27
2、.009CurativeeffectobservationofbutylflufenamateointmentpackagecombinedwithcompoundbetamethasonelocalinjectioninthetreatmentofprurigonodularisWANGDong,WANGQiang,RENKai-fang.ShenyangCitytheSeventhPeople’sHospital,Shenyang110003,China【Abstract]ObjectiveToobserveclinicaleffectofbutylflufena
3、mateointmentpackagecombinedwithcompoundbetamethasonelocalinjectioninthetreatmentofprurigonodularis.MethodsAtotalof100prurigonodularispatientswererandomlydividedintotreatmentgroupandcontrolgroup,with50casesineachgroup.Thetreatmentgroupreceivedbutylflufenamateointmentpackagecombinedwithco
4、mpoundbetamethasonelocalinjection,andthecontrolgroupreceivedsinglecompoundbetamethasonelocalinjection.Theircurativeeffectswerecompared.ResultsAttheendof2weeksoftreatment,thetotaleffectiveratewas98%inthetreatmentgroupand80%inthecontrolgroup.Thedifferencebetweenthetwogroupshadstatisticals
5、ignificance(x2=8.27,P0.05),具有可比性。1.2方法治療組以復(fù)方倍他米松注射液(商品名得寶松,上海先靈葆雅制藥有限公司)局部注射1次+次日夜間給予氟芬那酸丁酯(商品名布特,沈陽市抗生素廠)封包,1次/d,連續(xù)4周。復(fù)方倍他米松皮損內(nèi)注射方法[2]:將1ml復(fù)方倍他米松注射液用2%利多卡因或注射用水稀釋8倍備用,常規(guī)消毒皮損處待干,取稀釋液在結(jié)節(jié)處逐個封閉注射,以患者能耐受為度。次日夜間給予氟芬那酸丁酯軟膏封包,操作方法:穿戴無菌手套取氟芬那酸丁酯軟膏適量涂于每個皮損,藥膏厚度以0.2cm為宜,局部以保鮮膜封包,封包時間為2?3h。對照組僅以復(fù)方
6、倍他米松局部注射,1次/d,連續(xù)4周。在2周或4周內(nèi)痊愈者可停止用藥,兩組在2周末及4周末進(jìn)行療效判斷。1.3療效判定標(biāo)準(zhǔn)[3]痊愈:皮損消退〉95%,自覺癥狀消失;顯效:皮損消退75%?95%,自覺癥狀基本消失;有效:皮損消退50%?74%,自覺癥狀減退;無效:皮損消退